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N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Structure
CAS No.
110025-28-0
Chemical Name:
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
Synonyms
CS-2602;4OHNDtam;E/Z Endoxifen;Endoxifen (Z/E=3:2);Endoxifen(EE/Z=1:1);Endoxifen(E/Z=1: 1);(E /Z) Endoxifen HCl;Tamoxifen Impurity 16;4-hydroxy-N-desmethyltamoxifen;(E/Z)-N-desmethyl-4-hydroxy Tamoxifen
CBNumber:
CB61176584
Molecular Formula:
C25H27NO2
Molecular Weight:
373.49
MOL File:
110025-28-0.mol
MSDS File:
SDS
Modify Date:
2023/9/4 15:50:00

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Properties

Melting point 63-72°C
Boiling point 519.3±50.0 °C(Predicted)
Density 1.099±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform, Dichloromethane, DMSO, Methanol
form Solid
pka 9.38±0.15(Predicted)
color Light Brown to Light Purple

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
NFPA 704
0
3 0

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Chemical Properties,Uses,Production

Chemical Properties

Brown Foam

Uses

A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca

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N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Spectrum

4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol 4OHNDtam E/Z Endoxifen N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) 4-hydroxy-N-desmethyltamoxifen 4-[(E)-1-[4-(2-methylaminoethoxy)phenyl]-2-phenyl-but-1-enyl]phenol 4-[(Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) see H938500 (E /Z) Endoxifen HCl Endoxifen (Z/E=3:2) 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol Endoxifen(EE/Z=1:1) Endoxifen(E/Z=1: 1) 4-Hydroxy-N-Desmethyl Tamoxifen ((E/Z)-Endoxifen) Phenol,4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]- CS-2602 (E/Z)-N-desmethyl-4-hydroxy Tamoxifen 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol 4-Hydroxy-N-Desmethyl Tamoxifen (Endoxifen) (Mixture of Z and E Isomers) Tamoxifen Citrate Impurity 11 (4-Hydroxy-N-Desmethyl Tamoxifen) (Mixture of Z and E Isomers) Tamoxifen Impurity 16 inhibit,Parasite,Aromatase,Endoxifen,Inhibitor,Drug Metabolite,Estrogen Receptor/ERR 110025-28-0 Aromatics Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals