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4-HYDROXYTAMOXIFEN

4-HYDROXYTAMOXIFEN Structure
CAS No.
68047-06-3
Chemical Name:
4-HYDROXYTAMOXIFEN
Synonyms
hydroxytamoxifen;4-OHT;C05011;(Z)-4-OHT;ici79,280;(E)-4’4-Benzyloxy β4-HYDROXYTAMOXIFEN;TAMOXIFEN, 4-HYDROXY-;cis-4-Hydroxytamoxifen
CBNumber:
CB0754622
Molecular Formula:
C26H29NO2
Molecular Weight:
387.51
MOL File:
68047-06-3.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

4-HYDROXYTAMOXIFEN Properties

Melting point 105-107°C
Boiling point 513.45°C (rough estimate)
Density 1.1005 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. 2-8°C
solubility 95% ethanol: 20 mg/mL
pka 10.35±0.15(Predicted)
form powder
color white
Stability Stable. Store cool. Incompatible with strong oxidizing agents.
InChIKey TXUZVZSFRXZGTL-OCEACIFDSA-N
CAS DataBase Reference 68047-06-3

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H302-H350-H360FD-H410
Precautionary statements  P201-P202-P264-P273-P301+P312-P308+P313
Hazard Codes  Xn
Risk Statements  20/21/22-63
Safety Statements  22-23-36
WGK Germany  3
RTECS  SL1210000
NFPA 704
0
3 0

4-HYDROXYTAMOXIFEN price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) H7904 (Z)-4-Hydroxytamoxifen ≥98% Z isomer 68047-06-3 5MG ₹15209.13 2022-06-14 Buy
Sigma-Aldrich(India) H7904 (Z)-4-Hydroxytamoxifen ≥98% Z isomer 68047-06-3 25MG ₹60013.8 2022-06-14 Buy
Sigma-Aldrich(India) 579002 Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem A cell-permeable, active metabolite of Tamoxifen that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC b 68047-06-3 5MG ₹17860 2022-06-14 Buy
Sigma-Aldrich(India) 5.08225 InSolution Tamoxifen, 4-Hydroxy-, ( Z)- - CAS 68047-06-3 - Calbiochem A 10 mM (2 mg/516 μL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen in ethanol. 68047-06-3 2MG ₹9380 2022-06-14 Buy
Product number Packaging Price Buy
H7904 5MG ₹15209.13 Buy
H7904 25MG ₹60013.8 Buy
579002 5MG ₹17860 Buy
5.08225 2MG ₹9380 Buy

4-HYDROXYTAMOXIFEN Chemical Properties,Uses,Production

Chemical Properties

Powder

Uses

A hydroxylated analogue of tamoxifen with anti-estrogenic properties. A metabolite of Tamoxifen.

General Description

A cell-permeable, active metabolite of Tamoxifen (Cat. No. 579000) that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain. Also available as a 10 mM solution in EtOH (Cat. No. 508225).

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4-HYDROXYTAMOXIFEN Spectrum

trans-4-Hydroxytamoxifen, (Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol (Z)-3,4-Diphenyl-4-[4-[2-(dimethylamino)ethoxy]phenyl]-3-buten-1-ol 2-[4-[(E)-1-(4-Hydroxyphenyl)-2-phenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine 4-[(E)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol cis-4-Hydroxytamoxifen N,N-Dimethyl-2-[4-[(E)-1-(4-hydroxyphenyl)-2-phenyl-1-butenyl]phenoxy]ethanamine TAMOXIFEN 4-HYDROXY, (E) AND (Z) ISOMERS (50:50) (Z)-4-(1-[4-(Dimethylaminoethoxy)phenyl]-2-phenyl-1-butenyl)phenol C05011 4-OHT See H9711, H9712, or H9716 4-(1-(4-(dimethylaminoethoxy)phenyl)-2-phenyl-1-butenyl)phenol (Z)-4-OHT 4-HYDROXYTAMOXIFEN TAMOXIFEN, 4-HYDROXY- ici79,280 trans-4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-butenyl)phenol (E)-4&rsquo 4-[(1Z)-1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol Tamoxifen, 4-Hydroxy-, (Z)- - CAS 68047-06-3 - Calbiochem 4-Benzyloxy &beta Phenol, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]- Tamoxifen Citrate Impurity 9(4-Hydroxy Tamoxifen) 4-HYDROXYTAMOXIFEN USP/EP/BP hydroxytamoxifen trans-4-Hydroxytamoxifen inhibit,Estrogen Receptor/ERR,4-Hydroxytamoxifen,estrogen receptor,oral,CRISPR/Cas9,4Hydroxytamoxifen,Inhibitor,(Z)-Afimoxifene,nucleus translocation,4 Hydroxytamoxifen Tamoxifen Citrate Impurity 12 68047-06-3 C26H29NO2 BioChemical Antibiotics Antibiotics A to Z Antibiotics G-M Aromatics Metabolites & Impurities Drug Analogues Intermediates & Fine Chemicals Pharmaceuticals Steroids