4-Chloro-o-phenylenediamine
- CAS No.
- 95-83-0
- Chemical Name:
- 4-Chloro-o-phenylenediamine
- Synonyms
- 4-CHLORO-1,2-DIAMINOBENZENE;4-Chloro-ortho-phenylenediamine;ci76015;4-Cl-o-Pd;c.i.76015;NCI-C03292;C.I. 76015;ursololive6g;JACS-95-83-0;oro-o-phenyL
- CBNumber:
- CB6155430
- Molecular Formula:
- C6H7ClN2
- Molecular Weight:
- 142.59
- MOL File:
- 95-83-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/27 13:45:20
| Melting point | 70-73 °C(lit.) |
|---|---|
| Boiling point | 232.49°C (rough estimate) |
| Density | 1.2124 (rough estimate) |
| refractive index | 1.4877 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.52±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | 16 g/L (20 ºC) |
| BRN | 508472 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | BXIXXXYDDJVHDL-UHFFFAOYSA-N |
| CAS DataBase Reference | 95-83-0(CAS DataBase Reference) |
| IARC | 2B (Vol. 27, Sup 7) 1987 |
| NIST Chemistry Reference | 1,2-Benzenediamine, 4-chloro-(95-83-0) |
| EPA Substance Registry System | 4-Chloro-1,2-phenylenediamine (95-83-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H351 | |||||||||
| Precautionary statements | P201-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-40 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | SS8850000 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29215900 | |||||||||
| NFPA 704 |
|
4-Chloro-o-phenylenediamine price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 108871 | 4-Chloro-o-phenylenediamine 97% | 95-83-0 | 5G | ₹2067.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 108871 | 4-Chloro-o-phenylenediamine 97% | 95-83-0 | 25G | ₹7263.58 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C0255 | 4-Chloro-1,2-phenylenediamine min. 97.0 % | 95-83-0 | 5G | ₹2900 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C0255 | 4-Chloro-1,2-phenylenediamine min. 97.0 % | 95-83-0 | 25G | ₹6100 | 2022-05-26 | Buy |
4-Chloro-o-phenylenediamine Chemical Properties,Uses,Production
Chemical Properties
4-Chloro-o-phenylenediamine is a brown crystalline powder or leaflets from water; freezing/melting point 67-73°C; also reported in lit. @ 76°C. Slightly soluble in water. soluble in benzene, very soluble in ethanol, ether.
Uses
4-Chloro-o-phenylenediamine can be used as an oxidation base for dye preparation, as a chemical intermediate to produce 5-chlorobenzotriazole, as a curing agent for epoxy resins, as a reagent in gas chromatography, and to synthesize experimental pharmaceuticals. It has been used as a chemical intermediate in dye production and was patented as a hair-dye component, but there is no evidence that it is currently used in the United States for these purposes (IARC 1982, HSDB 2009).
Production Methods
Commercial production of 4-chloro-o-PDA in the United
States was first reported in 1941. About 0.45–4.5 thousand kg
was produced by a U.S. company in 1977. It was also
produced by one company in the Federal Republic of
Germany. This compound has been patented as a hair dye
component, fur dyes, inks, and hair coloring formulations,
and is believed to be used to produce 5-chlorobenzotriazole,
an isomer of which is a photographic chemical.
The primary routes of potential human exposure to 4-
chloro-o-PDA are inhalation and dermal contact during its
production. Consumer exposure may occur from use of hair
dyes or products made from 5-chlorobenzotriazole.
Definition
ChEBI: 4-Chloro-ortho-phenylenediamine is a member of monochlorobenzenes. Undergoes cyclizations and cyclocondensations to form benzimidazoles.
General Description
4-chloro-o-phenylenediamine appears as brown crystalline solid or powder. (NTP, 1992)
Air & Water Reactions
4-Chloro-1,2-diaminobenzene may be sensitive to prolonged exposure to air and light. Insoluble in water.
Reactivity Profile
4-Chloro-1,2-diaminobenzene is incompatible with strong oxidizers. 4-Chloro-1,2-diaminobenzene reacts with alpha-ketoacids to form quinoxalones.
Fire Hazard
Flash point data for 4-Chloro-1,2-diaminobenzene are not available. 4-Chloro-1,2-diaminobenzene is probably combustible.
Safety Profile
Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cland NOx. See also AROMATIC AMINES.
Potential Exposure
This organochlorine material has been patented as a hair dye component. It is believed to be used in production of photographic chemicals. In varying degrees, organochlorines are absorbed from the gut and also by the lung and across the skin.
Carcinogenicity
4-Chloro-o-phenylenediamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity fromstudies in experimental animals.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Purification Methods
Recrystallise the diamine from pet. ether. [Beilstein 13 IV 68.]
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Light sensitive. It reacts with alpha-ketoacids to form quinoxalones or benzopyrazines.
Waste Disposal
Disposal of unused product must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of appropriate protective equipment. For proper handling and disposal, always comply with federal, state, and local regulations.
4-Chloro-o-phenylenediamine Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Shree Ganesh Dye Chem | +91 079-26872726 | Gujarat, India | 97 | 58 | Inquiry |
| SynthoCascade Research Laboratories | +91-9440962500 +91-9440962500 | Telangana, India | 284 | 58 | Inquiry |
| Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
| REDDY N REDDY PHARMACEUTICALS | +91-9848096759 +91-9848096759 | Hyderabad, India | 1989 | 58 | Inquiry |
| Chemox Chemopharma Industries | +91-9909083070 +91-9824151570 | Gujarat, India | 13 | 58 | Inquiry |
| AATAMI Molecular Research Laboratories Pvt Ltd (AMRL) | +91-8985184986 +91-8148739767 | Telangana, India | 985 | 58 | Inquiry |
| Technichem Organics Pvt. Ltd | 91-79-27544346 | Gujarat, India | 31 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |