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Spermine

Spermine Structure
CAS No.
71-44-3
Chemical Name:
Spermine
Synonyms
SPERMINE TETRAHYDROCHLORIDE;Spermin;NEURIDINE HYDROCHLORIDE;MUSCULAMINE HYDROCHLORIDE;DJtPAT;Spermine;NSC 268508;Spermine,97%;Spermine >98%;SOYASAPONIN IV(SH)
CBNumber:
CB6275334
Molecular Formula:
C10H26N4
Molecular Weight:
202.34
MOL File:
71-44-3.mol
MSDS File:
SDS
Modify Date:
2024/8/7 19:09:42
Request For Quotation

Spermine Properties

Melting point 28-30 (lit.)
Boiling point 150 °C/5 mmHg (lit.)
Density 0.937
refractive index 1.4850 (estimate)
Flash point >230 °F
storage temp. 2-8°C
solubility H2O: 1 M at 20 °C, clear, colorless
form powder
pka 10.88±0.19(Predicted)
color Colorless to off-white
Water Solubility Soluble in chloroform, methanol, water and lower alcohols. Insoluble in ether, benzene and petroleum ether.
Sensitive Air Sensitive & Hygroscopic
Merck 14,8743
BRN 1751791
Stability Hygroscopic
InChIKey PFNFFQXMRSDOHW-UHFFFAOYSA-N
LogP -0.543 (est)
CAS DataBase Reference 71-44-3(CAS DataBase Reference)
NIST Chemistry Reference Spermine(71-44-3)
EPA Substance Registry System 1,4-Butanediamine, N,N'-bis(3-aminopropyl)- (71-44-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H318-H314
Precautionary statements  P260h-P301+P330+P331-P303+P361+P353-P405-P501a-P280-P305+P351+P338-P310
Hazard Codes  Xi,C
Risk Statements  36/38-34
Safety Statements  26-36-45-36/37/39-27
RIDADR  UN 3259 8/PG 2
WGK Germany  3
RTECS  EJ7230000
F  3-10
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29212900
NFPA 704
1
3 1

Spermine price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S4264 Spermine suitable for cell culture, BioReagent 71-44-3 1G ₹6397.58 2022-06-14 Buy
Sigma-Aldrich(India) S3256 Spermine ≥97% 71-44-3 1G ₹6711.5 2022-06-14 Buy
Sigma-Aldrich(India) S4264 Spermine suitable for cell culture, BioReagent 71-44-3 5G ₹27051.68 2022-06-14 Buy
Sigma-Aldrich(India) S3256 Spermine ≥97% 71-44-3 5G ₹20166.98 2022-06-14 Buy
Sigma-Aldrich(India) S3256 Spermine ≥97% 71-44-3 25G ₹66400.55 2022-06-14 Buy
Product number Packaging Price Buy
S4264 1G ₹6397.58 Buy
S3256 1G ₹6711.5 Buy
S4264 5G ₹27051.68 Buy
S3256 5G ₹20166.98 Buy
S3256 25G ₹66400.55 Buy

Spermine Chemical Properties,Uses,Production

Description

Spermine is an endogenous polyamine synthesized from the reaction of spermidine with decarboxylated S-adenosylmethionine in the presence of the enzyme spermine synthase and is required for eukaryotic cell growth and protein synthesis. Intracellular spermine blocks inward rectifying K+ channels, whereas extracellular spermine acts as a mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Spermine has neuroprotective and anti-inflammatory effects and functions as a free radical scavenger to prevent DNA damage by reactive oxygen species.

Chemical Properties

White to slightly off-white powder crysta

Uses

Binds to the polyamine modulatory site of NMDA Spermine is essential for both normal and neoplastic tissue growth. It is involved in the modulation of calcium-dependent immune processes. It plays an important role in cellular proliferation and differentiation as well as inhibits neuronal nitric oxide synthase (nNOS).

Definition

ChEBI: A polyazaalkane that is tetradecane in which the carbons at positions 1, 5, 10 and 14 are replaced by nitrogens. Spermine has broad actions on cellular metabolism.

General Description

Spermine?is a polyamine, which functions as a free radical scavenger. It modulates gene expression, chromatin stabilization and prevents DNA damage. Spermine inhibits endonuclease-mediated DNA fragmentation.

Spermine Preparation Products And Raw materials

Raw materials

Coconut oil

Preparation Products

3-aminopropanal N2,N3,N4-TRIS-(TERT-BUTYLOXYCARBONYL)-1,5,10,14-TETRA-AZA-QUATRODECANE SPERMINE TETRAHYDROCHLORIDE Spermidine

Spermine Suppliers

Global( 325)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
Hangzhou Zelixir Biotech Co., Ltd. +8618867646786 China 232 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12585 58 Inquiry
Shaanxi Haibo Biotechnology Co., Ltd +undefined18602966907 China 1000 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20290 58 Inquiry
Hangzhou Hyper Chemicals Limited +86-0086-57187702781 +8613675893055 China 295 58 Inquiry
Supplier Advantage
Otto Chemie Pvt. Ltd. 58
CLEARSYNTH LABS LTD. 58
Sisco Research Laboratories Pvt. Ltd. 58
Triveni chemicals 58
CHEMSWORTH 30
Hangzhou Zelixir Biotech Co., Ltd. 58
Hebei Mojin Biotechnology Co., Ltd 58
Shaanxi Haibo Biotechnology Co., Ltd 58
Henan Fengda Chemical Co., Ltd 58
Hangzhou Hyper Chemicals Limited 58

Spermine Spectrum

Spermine(71-44-3)1HNMRSpermine(71-44-3)IR1

71-44-3(Spermine)Related Search:

Histamine Ethanethiol Diallylamine POLYAMINOPROPYL BIGUANIDE N,N-Diisopropylethylamine
Diisopropylamine 1,4-DIAMINOBUTANE Spermidine Triallylamine Succinic acid
Allylamine L(+)-Arginine O,O-Dimethyl phosphoramidothioate SPERMINE TETRAHYDROCHLORIDE SPERMINE TETRAHYDROCHLORIDE, [TERMINAL METHYLENE-3H]
Spermine [14C]SPERMINE TETRAHYDROCHLORIDE
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SPERMINE TETRAHYDROCHLORIDE SPERMINE HYDROCHLORIDE n,n’-bis(3-aminopropyl)-4-butanediamine n,n’-bis(3-aminopropyl)-4-diaminobutane Spermin N,N'-BIS(3-AMINOPROPYL)-1,4-BUTANEDIAMINE 4 H CL N,N'-BIS(3-AMINOPROPYL)-1,4-BUTANEDIAMINE TETRAHYDROCHLORIDE N,N'-BIS-(3-AMINOPROPYL)-1,4-DIAMINOBUTANE TETRAHYDROCHLORIDE N,N'-BIS(3-AMINOPROPYL)-BUTANE-1,4-DIAMINE TETRAHYDROCHLORIDE NEURIDINE HYDROCHLORIDE NEURIDINE TETRAHYDROCHLORIDE MUSCULAMINE HYDROCHLORIDE MUSCULAMINE TETRAHYDROCHLORIDE Spermine SOYASAPONIN IV(SH) Spermine,N,N′-Bis(3-aminopropyl)-1,4-diaminobutane, Gerontine, Musculamine, Neuridine Spermine >98% N,N'-Bis(3-aminopropyl)-1,4-butanediamine N1,N1'-(butane-1,4-diyl)bis(propane-1,3-diaMine) GERONTINE TETRAHYDROCHLORIDE DIAMINOPROPYLTETRAMETHYLENEDIAMINE HYDROCHLORIDE 1,4-BIS(AMINOPROPYL)BUTANEDIAMINE TETRAHYDROCHLORIDE 4,9-diazadodecamethylenediamine N,N-Bis(3-aminopropyl)-1,4-diaminobutane~Gerontine~Musculamine~Neuridine Spermine N,N-Bis(3-aminopropyl)-1,4-diaminobutane SPERMINE FREE BASE CELL CULTURE TESTED Spermine,97% Sperminedihydrate,97% BIS(3-AMINOPROPYL)-1,4-BUTANEDIAMINE NSC 268508 SPERMINE FREE BASE extrapure 1,4-Bis(aminopropyl)butanediamine 1,4-Butanediamine, N,N'-bis(3-aminopropyl)- 1,4-Diaminobutane, N,N'-bis(3-aminopropyl)- 4,9-Diaza-1,12-dodecanediamine 4,9-Diazadodecane-1,12-diamine N,NBis(2-aminopropyl)-1,4-butane-diamine, N,NBis(2-aminopropyl)tetramethylenediamine SPERMINE >= 99.0% (GC) bis(propane-1,3-diamine) N1,N1'-(Butane-1,4-diyl) 1,4-Butanediamine, N1,N4-bis(3-aminopropyl)- DJtPAT Spermine CAS 71-44-3 with Best Price Fast Delivery Good Quality Spermine (NSC-268508 (3-aminopropyl)({4-[(3-aminopropyl)amino]butyl}) amine Spermine, ≥99% (GC) N,N'-bis(3-aminopropyl)butane-1,4-diamine N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) Gerontine|||Musculamine|||4,9-Diaza-1,12-dodecanediamine|||NSC 268508|||Neuridine 71-44-3 77-44-3 H2NCH23NHCH23NH2 NH2CH23NHCH24NHCH23NH2 H2NCNHNHCH24NH2 C10H26N4 Amino Acids and Peptides Biochemicals and Reagents BioChemical