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5-Fluorouridine

5-Fluorouridine  Structure
CAS No.
316-46-1
Chemical Name:
5-Fluorouridine
Synonyms
FUR;5-FU;FURD;5-fur;5-FUrd;NSC 146604;NSC 519273;FLUOROURIDINE;5-FLUOROIDINE;5-fluoro-uridin
CBNumber:
CB6346346
Molecular Formula:
C9H11FN2O6
Molecular Weight:
262.19
MOL File:
316-46-1.mol
MSDS File:
SDS
Modify Date:
2024/11/17 8:48:38

5-Fluorouridine Properties

Melting point 182-184 °C
alpha 17 º (c=2, water 25 ºC)
Density 1.4200 (estimate)
refractive index 18 ° (C=1, H2O)
storage temp. 2-8°C
solubility Soluble in DMSO (up to 50 mg/ml), in Water (up to 50 mg/ml), or in Ethanol (up to 6 mg/ml with warming)
form Powder
pka 7.63±0.10(Predicted)
color White
Water Solubility soluble
BRN 33662
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO, distilled water or ethanol may be stored at -20°C for up to 3 months.
CAS DataBase Reference 316-46-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H341-H373
Precautionary statements  P201-P202-P260-P280-P308+P313-P405-P501-P501a
Hazard Codes  Xn,Xi
Risk Statements  40-68-36/37/38
Safety Statements  22-26-36/37-36/37/39-27-24/25
WGK Germany  3
RTECS  YU8050000
10
Hazard Note  Harmful
HS Code  29349990

5-Fluorouridine price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) F5130 5-Fluorouridine proapoptotic anitproliferative plant growth regulator 316-46-1 100MG ₹8779.08 2022-06-14 Buy
Sigma-Aldrich(India) F5130 5-Fluorouridine proapoptotic anitproliferative plant growth regulator 316-46-1 250MG ₹17384.95 2022-06-14 Buy
Sigma-Aldrich(India) F5130 5-Fluorouridine proapoptotic anitproliferative plant growth regulator 316-46-1 1G ₹49773.35 2022-06-14 Buy
TCI Chemicals (India) F0636 5-Fluorouridine 316-46-1 1G ₹3800 2022-05-26 Buy
TCI Chemicals (India) F0636 5-Fluorouridine 316-46-1 5G ₹6200 2022-05-26 Buy
Product number Packaging Price Buy
F5130 100MG ₹8779.08 Buy
F5130 250MG ₹17384.95 Buy
F5130 1G ₹49773.35 Buy
F0636 1G ₹3800 Buy
F0636 5G ₹6200 Buy

5-Fluorouridine Chemical Properties,Uses,Production

Chemical Properties

White Powder

Uses

5-Fluorouridine exhibits anticancer activity. It is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs. It is an active metabolite of Doxifluridine.

Definition

ChEBI: An organofluorine compound that is uridine bearing a fluoro substituent at position 5 on the uracil ring.

General Description

5-Fluorouridine (FUrd) is a fluoropyrimidine nucleoside analog and a cell-permeable modified RNA precursor.

Purification Methods

5Fluorouridine is recrystallised from EtOH/Et2O and dried at 100o in a vacuum. UV: max 269nm (pH 7.2, H2O), 270nm (pH 14, H2O). [Liang et al. Mol Pharmacol 21 224 1982, Beilstein 24 III/IV 1231.]

5-Fluorouridine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 227)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6768 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4315 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6088 58 Inquiry
Capot Chemical Co.,Ltd. +86-(0)57185586718 +86-13336195806 China 29791 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49374 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29811 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32080 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. +86-0551-65418671 +8618949823763 China 34553 58 Inquiry
1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1 5-fluoro-uridin 5-fur Uridine, 5-fluoro- FURD FLUOROURIDINE 1-(3,4-DIHYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-5-FLUORO-1H-PYRIMIDINE-2,4-DIONE 5-FLUORO-1-(BETA-D-RIBOFURANOSYL)URACIL 5-FU 5-FLUOROURACIL-1BETA-D-RIBOFURANOSIDE 2,4-DIHYDROXY-5-FLUORO-1-BETA-D-RIBOFURANOSYLPYRIMIDINE 5-fluorouracil 1β-d-ribofuranoside 5-Fluorouridine97% 5-FLUOROURIDINE, 98+% 5-Fluorouridine 5-FLUOROIDINE (2'R,3'R,4'S,5'R)-1-(3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-fluoro-1H-pyrimidine-2,4-dione 1-(beta-D-Ribofuranosyl)-5-fluorouracil 5-FLUOROURIDINE extrapure 5-Fluorouracil 1β-D-ribofuranoside, FUrd 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione 5-FLUOROURIDINE, 99+% FUR 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-fluoropyriMidine-2,4(1H,3H)-dione 5-FUrd NSC 146604 NSC 519273 FUrd 1-(beta-D-Ribofuranosyl)-5-fluorouracil 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3 5-Fluorouridine> 5-Fluorouridine USP/EP/BP 5-Fluorouridine (5-FUrd) extrapure, 98% 1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]-5-fluoropyrimidine-2,4-dione 5-Fluorouridine, impurity of 5-fluorouracil 5- fluorouracil nucleoside 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione 316-46-1 C9H11FN2O6 Analytical Chromatography Product Catalog Alphabetic BioChemical Analytical Standards Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs FA - FL Fluorine series Biochemistry Chemical Reagents for Pharmacology Research Nucleosides and their analogs Nucleosides, Nucleotides & Related Reagents Bases & Related Reagents Nucleotides Nucleotides and Nucleosides Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals Pyrimidine Pyridines, Pyrimidines, Purines and Pteredines bc0001