o-Cresolphthalein
![o-Cresolphthalein Structure](CAS/GIF/596-27-0.gif)
- CAS No.
- 596-27-0
- Chemical Name:
- o-Cresolphthalein
- Synonyms
- cresolphthalein;o-Cresolphalein;o-Cresolphthalei;o-cresolphtaleine;O-CRESOLPHTHALEIN;O-Cresolphtnalein;3,3-Bis(4-hydroxy-;Cresolphthanalein;o-CRESOLPHTHLALEIN;TIMTEC-BB SBB006498
- CBNumber:
- CB6392671
- Molecular Formula:
- C22H18O4
- Molecular Weight:
- 346.38
- MOL File:
- 596-27-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/30 14:17:11
Melting point | 223-225 °C |
---|---|
Boiling point | 401.12°C (rough estimate) |
Density | 1.1425 (rough estimate) |
refractive index | 1.4400 (estimate) |
solubility | Solubility Slightly soluble in water; soluble in ethanol |
form | powder |
pka | 9.40(at 25℃) |
color | Clear colorless |
PH Range | 8.2 (colorless) - 9.8 (violet/red) |
Water Solubility | slightly soluble |
λmax | 566nm, 381nm |
Merck | 14,2576 |
BRN | 310554 |
Major Application | Sensors, display device, photoresists, recording materials, imaging materials, authentication system for secure documents, decoder system, lithium cells, electroplating process, inks, markers, toners, correction fluid, paints, adhesives, floor coatings, gas leaking detector for safety in industries, toys, food storage, diapers, determination of calcium, lotions, urine analysis test strips, drugs, blood analysis |
InChIKey | CPBJMKMKNCRKQB-UHFFFAOYSA-N |
CAS DataBase Reference | 596-27-0(CAS DataBase Reference) |
EPA Substance Registry System | 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3-methylphenyl)- (596-27-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() GHS02,GHS07,GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H225-H319-H335+H336-H340-H360-H372-H373 | |||||||||
Precautionary statements | P201-P202-P210-P233-P240-P241+P242+P243-P260-P264-P270-P271-P280-P303+P361+P353-P304+P340+P312-P305+P351+P338+P337+P313-P308+P313-P403+P233-P405-P501 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 40-36/37/38-20/21/22 | |||||||||
Safety Statements | 36/37-36-26 | |||||||||
RIDADR | 1170 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | SM8390000 | |||||||||
TSCA | Yes | |||||||||
HS Code | 3822.19.0080 | |||||||||
NFPA 704 |
|
o-Cresolphthalein price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C85778 | o-Cresolphthalein indicator grade | 596-27-0 | 10G | ₹4817.13 | 2022-06-14 | Buy |
TCI Chemicals (India) | C0404 | o-Cresolphthalein | 596-27-0 | 25G | ₹3500 | 2022-05-26 | Buy |
TCI Chemicals (India) | C0404 | o-Cresolphthalein | 596-27-0 | 100G | ₹9100 | 2022-05-26 | Buy |
SRL | 29121 | o-Cresolphthalein AR, 95% | 596-27-0 | 5Gms | ₹160 | 2022-05-26 | Buy |
SRL | 29121 | o-Cresolphthalein AR, 95% | 596-27-0 | 25Gms | ₹580 | 2022-05-26 | Buy |
o-Cresolphthalein Chemical Properties,Uses,Production
Chemical Properties
white to pink or beige to tan powder. soluble in ethanol, ether, glacial acetic acid, soluble in dilute alkali and turns purple, slightly soluble in water, hardly soluble in benzene.
Uses
O-Cresolphthalein has been used as a component in calcifying media for calcification assay. It is also used as an indicator (pH range, 8.2 colorless, 9.8 red) and analytical reagent.
Application
O-Cresolphthalein is a gadolinium chelate that is used as a contrast agent for magnetic resonance imaging (MRI) of the brain, spine, and joints. The gadolinium ion is bound to the cresol molecule, which has an attached hydroxyl group. This complex attaches to the phosphorous pentoxide and creates a precipitate of metal hydroxides in the presence of water and sodium carbonate. O-Cresolphthalein is also used in clinical pathology to measure glomerular filtration rate (GFR), which is important for diagnosing renal disease. MRI scans are used to diagnose osteogenic genes that are associated with bone diseases such as osteoporosis.
Biochem/physiol Actions
o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.
o-Cresolphthalein Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Arnish Laborates Pvt Ltd | +91 7208475595 | Maharashtra, India | 187 | 58 | Inquiry |
JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
Esjay Chemicals | +919820452929 | Maharashtra, India | 110 | 58 | Inquiry |
GSP Dyes and Chemicals Pvt.Ltd | +91-22-28144802 +91-2228144802 | Maharashtra, India | 79 | 58 | Inquiry |
Anubhav Business Corporation | +91-2228014519 +91-2228014999 | Maharashtra, India | 119 | 58 | Inquiry |
Mehta Enterprise | 08068442230Ext 607 | Mumbai, India | 155 | 58 | Inquiry |
Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
Suvchem | 91-22-28725393 | Maharashtra, India | 180 | 58 | Inquiry |
Sisco Resech Laboratories Private Limited | +91-22-4268 5800 | Mumbai, India | 655 | 58 | Inquiry |
Maitree Chemicals | 08048371810Ext 121 | Maharashtra, India | 29 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Arnish Laborates Pvt Ltd | 58 |
JSK Chemicals | 58 |
Esjay Chemicals | 58 |
GSP Dyes and Chemicals Pvt.Ltd | 58 |
Anubhav Business Corporation | 58 |
Mehta Enterprise | 58 |
Anand Agencies | 58 |
Suvchem | 58 |
Sisco Resech Laboratories Private Limited | 58 |
Maitree Chemicals | 58 |
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