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o-Cresolphthalein

o-Cresolphthalein Structure
CAS No.
596-27-0
Chemical Name:
o-Cresolphthalein
Synonyms
cresolphthalein;o-Cresolphalein;o-Cresolphthalei;o-cresolphtaleine;O-CRESOLPHTHALEIN;O-Cresolphtnalein;3,3-Bis(4-hydroxy-;Cresolphthanalein;o-CRESOLPHTHLALEIN;TIMTEC-BB SBB006498
CBNumber:
CB6392671
Molecular Formula:
C22H18O4
Molecular Weight:
346.38
MOL File:
596-27-0.mol
MSDS File:
SDS
Modify Date:
2024/7/30 14:17:11

o-Cresolphthalein Properties

Melting point 223-225 °C
Boiling point 401.12°C (rough estimate)
Density 1.1425 (rough estimate)
refractive index 1.4400 (estimate)
solubility Solubility Slightly soluble in water; soluble in ethanol
form powder
pka 9.40(at 25℃)
color Clear colorless
PH Range 8.2 (colorless) - 9.8 (violet/red)
Water Solubility slightly soluble
λmax 566nm, 381nm
Merck 14,2576
BRN 310554
Major Application Sensors, display device, photoresists, recording materials, imaging materials, authentication system for secure documents, decoder system, lithium cells, electroplating process, inks, markers, toners, correction fluid, paints, adhesives, floor coatings, gas leaking detector for safety in industries, toys, food storage, diapers, determination of calcium, lotions, urine analysis test strips, drugs, blood analysis
InChIKey CPBJMKMKNCRKQB-UHFFFAOYSA-N
CAS DataBase Reference 596-27-0(CAS DataBase Reference)
EPA Substance Registry System 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3-methylphenyl)- (596-27-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07,GHS08
Signal word  Danger
Hazard statements  H225-H319-H335+H336-H340-H360-H372-H373
Precautionary statements  P201-P202-P210-P233-P240-P241+P242+P243-P260-P264-P270-P271-P280-P303+P361+P353-P304+P340+P312-P305+P351+P338+P337+P313-P308+P313-P403+P233-P405-P501
Hazard Codes  Xn
Risk Statements  40-36/37/38-20/21/22
Safety Statements  36/37-36-26
RIDADR  1170
WGK Germany  3
RTECS  SM8390000
TSCA  Yes
HS Code  3822.19.0080
NFPA 704
0
1 0

o-Cresolphthalein price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C85778 o-Cresolphthalein indicator grade 596-27-0 10G ₹4817.13 2022-06-14 Buy
TCI Chemicals (India) C0404 o-Cresolphthalein 596-27-0 25G ₹3500 2022-05-26 Buy
TCI Chemicals (India) C0404 o-Cresolphthalein 596-27-0 100G ₹9100 2022-05-26 Buy
SRL 29121 o-Cresolphthalein AR, 95% 596-27-0 5Gms ₹160 2022-05-26 Buy
SRL 29121 o-Cresolphthalein AR, 95% 596-27-0 25Gms ₹580 2022-05-26 Buy
Product number Packaging Price Buy
C85778 10G ₹4817.13 Buy
C0404 25G ₹3500 Buy
C0404 100G ₹9100 Buy
29121 5Gms ₹160 Buy
29121 25Gms ₹580 Buy

o-Cresolphthalein Chemical Properties,Uses,Production

Chemical Properties

white to pink or beige to tan powder. soluble in ethanol, ether, glacial acetic acid, soluble in dilute alkali and turns purple, slightly soluble in water, hardly soluble in benzene.

Uses

O-Cresolphthalein has been used as a component in calcifying media for calcification assay. It is also used as an indicator (pH range, 8.2 colorless, 9.8 red) and analytical reagent.

Application

O-Cresolphthalein is a gadolinium chelate that is used as a contrast agent for magnetic resonance imaging (MRI) of the brain, spine, and joints. The gadolinium ion is bound to the cresol molecule, which has an attached hydroxyl group. This complex attaches to the phosphorous pentoxide and creates a precipitate of metal hydroxides in the presence of water and sodium carbonate. O-Cresolphthalein is also used in clinical pathology to measure glomerular filtration rate (GFR), which is important for diagnosing renal disease. MRI scans are used to diagnose osteogenic genes that are associated with bone diseases such as osteoporosis.

Biochem/physiol Actions

o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.

o-Cresolphthalein Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 337)Suppliers
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Arnish Laborates Pvt Ltd +91 7208475595 Maharashtra, India 187 58 Inquiry
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Maitree Chemicals 08048371810Ext 121 Maharashtra, India 29 58 Inquiry
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