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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Endocrinology & Hormones >RAAS inhibitors >MOEXIPRIL HYDROCHLORIDE

MOEXIPRIL HYDROCHLORIDE

MOEXIPRIL HYDROCHLORIDE Structure
CAS No.
82586-52-5
Chemical Name:
MOEXIPRIL HYDROCHLORIDE
Synonyms
CI-925;Perdix;SPM-925;Univasc;Fempress;RS-10085;RS-10085-197;MOEXIPRIL HYDROCHLORIDE;Moexipril HCl (RS-10085);Moexipril hydrochloride, >=99%
CBNumber:
CB6500845
Molecular Formula:
C27H35ClN2O7
Molecular Weight:
535.03
MOL File:
82586-52-5.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:14
Request For Quotation

MOEXIPRIL HYDROCHLORIDE Properties

Melting point 141-1610C
alpha D23 +34.2° (c = 1.1 in ethanol)
storage temp. 2-8°C
solubility H2O: soluble32mg/mL
form powder
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273-P391-P501
Hazard Codes  N
Risk Statements  50
Safety Statements  60
RIDADR  UN 3077 9/PG 3
WGK Germany  3
RTECS  NW7174500
HS Code  2933492250
NFPA 704
0
3 0

MOEXIPRIL HYDROCHLORIDE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) M0821 Moexipril hydrochloride powder, ≥98% (HPLC) 82586-52-5 50MG ₹19658.2 2022-06-14 Buy
Sigma-Aldrich(India) M0821 Moexipril hydrochloride powder, ≥98% (HPLC) 82586-52-5 100MG ₹37367.9 2022-06-14 Buy
Product number Packaging Price Buy
M0821 50MG ₹19658.2 Buy
M0821 100MG ₹37367.9 Buy

MOEXIPRIL HYDROCHLORIDE Chemical Properties,Uses,Production

Description

Moexipril hydrochloride is a novel ACE inhibitor first marketed in the U.S.A. for the treatment of hypertension as a monotherapy and as a second-line therapy in combination with diuretics or calcium antagonists. Like other ACE inhibitors, moexipril is a prodrug that is converted in the liver to its diacid moexiprilat which is the active agent. Moexipril displays a higher in vitro inhibitory potency to ACE than enalapril although its effectiveness in reduction of blood pressure in hypertensive patients is similar to that seen with enalapril. It is orally active with a rapid onset and prolonged duration of action. Excellent tolerability has been reported. Moexipril is distinguished by its lower cost than other marketed ACE inhibitors.

Chemical Properties

Crystalline Solid

Uses

Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril

Hazard

Moderately toxic by ingestion.

Biological Activity

Angiotensin-converting enzyme (ACE) inhibitor that is hydrolyzed in the liver to the active metabolite moexiprilat (IC 50 values are 2.1 and 2700 nM for moexiprilat and moexipril respectively). Antihypertensive; decreases mean blood pressure in the spontaneous hypertensive rat (SHR). Also blocks degradation of bradykinin into inactive metabolites.

MOEXIPRIL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

ethyl 4-bromo-4-phenyl-butanoate Triethylamine 1-Hydroxybenzotriazole

Preparation Products

MOEXIPRIL HYDROCHLORIDE Suppliers

Global( 145)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
GLENMARK LIFE SCIENCES LTD +91 22 4018 9999 New Delhi, India 103 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12459 58 Inquiry
Ouhuang Engineering Materials (Hubei) Co., Ltd +86-86177 China 2952 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Hebei Guanlang Biotechnology Co., Ltd. +86-19930503282 China 8828 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Supplier Advantage
GLENMARK LIFE SCIENCES LTD 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Hebei Mojin Biotechnology Co., Ltd 58
Ouhuang Engineering Materials (Hubei) Co., Ltd 58
Capot Chemical Co.,Ltd. 60
career henan chemical co 58
Hebei Guanlang Biotechnology Co., Ltd. 58
Chongqing Chemdad Co., Ltd 58

MOEXIPRIL HYDROCHLORIDE Spectrum

MOEXIPRIL HYDROCHLORIDE(82586-52-5)1HNMR

82586-52-5(MOEXIPRIL HYDROCHLORIDE)Related Search:

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Ramipril Isoquinoline-1-carboxylic acid Moexipril
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(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride 2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylicacidhydrochloride 3-Isoquinolinecarboxylicacid,2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]aMino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-,hydrochloride (1:1), (3S)- (3S)- 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid,hydrochloride (1:1) RS-10085 Moexipril Hydrochloride (100 mg) Moexipril hydrochloride, >=99% (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenyl-d5-propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid Hydrochloride CI-925 Fempress Perdix RS-10085-197 SPM-925 Univasc (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic Acid Hydrochloride (3S)-2-[(2S)-2-[[(1S)-1-carbethoxy-3-phenyl-propyl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenyl-butan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid hydrochloride MOEXIPRIL HYDROCHLORIDE UNIVASC;RS10085;RS 10085;RS-10085 (3S)-2-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-Phenyl-Propyl]Amino]Propanoyl]-6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinoline-3-Carboxylic Acid Hydrochloride 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, hydrochloride MOEXIPRIL HYDROCHLORIDE USP/EP/BP (S)-2-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride Moexipril HCl (RS-10085) (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan -2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetr ahydroisoquinoline-3-carboxylic acid hydrochloride Moexipril HydrochlorideQ: What is Moexipril Hydrochloride Q: What is the CAS Number of Moexipril Hydrochloride Q: What is the storage condition of Moexipril Hydrochloride Q: What are the applications of Moexipril Hydrochloride Moexipril Hydrochloride (1445426) orally active,Apoptosis,Ischemic brain injury,inhibit,hepatic disease,RS10085,Angiotensin-converting Enzyme (ACE),hydrochlorothiazide,essential hypertension,Moexipril hydrochloride,antihypertensive,moexiprilat,angiotensin II,cardiovascular disease,RS 10085,Inhibitor,hypertension,Moexipril 82586-52-5 C27H34N2O7HCl C27H35N2O7Cl C27H35ClN2O7 C27H34N2O7ClH Aromatics Inhibitors API Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents Coronavirus