TRIPELENNAMINE HYDROCHLORIDE
- CAS No.
- 154-69-8
- Chemical Name:
- TRIPELENNAMINE HYDROCHLORIDE
- Synonyms
- Azaron;TRIPELENNAMINE HCL;ReCovr;dehistin;piristin;Ahistamin;pyrinamine;stanzamine;tri-tumine;pyrabenzamine
- CBNumber:
- CB7126697
- Molecular Formula:
- C16H22ClN3
- Molecular Weight:
- 291.82
- MOL File:
- 154-69-8.mol
- Modify Date:
- 2024/7/2 8:55:15
Melting point | 192-193℃ |
---|---|
Density | 1.20 |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO : 25 mg/mL (85.67 mM; Need ultrasonic) |
form | Solid |
color | White to off-white |
EPA Substance Registry System | Tripelennamine hydrochloride (154-69-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38 |
Safety Statements | 26-36 |
WGK Germany | 3 |
RTECS | US3150000 |
HS Code | 2933399090 |
Toxicity | LD50 in mice (mg/kg): 47 i.p. (Walker) |
TRIPELENNAMINE HYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Tripelennamine is a first-generation antihistamine, used in the treatment of asthma, hay fever, and urticaria.
General Description
Tripelennamine hydrochlorideis a white crystalline powder that darkensslowly on exposure to light. The salt is soluble in water(1:0.77) and in alcohol (1:6). It has a pKa of about 9, and a0.1% solution has a pH of about 5.5.
Tripelennamine, the first ethylenediamine developed inthe United States and is well absorbed when given orally. Itappears to be as effective as diphenhydramine and may havethe advantage of fewer and less severe side reactions.Drowsiness may occur, however, and may impair the abilityto perform tasks requiring alertness. The concurrent use ofalcoholic beverages should be avoided.
Air & Water Reactions
Water soluble.
Reactivity Profile
TRIPELENNAMINE HYDROCHLORIDE behaves as a weak organic acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Fire Hazard
Flash point data for TRIPELENNAMINE HYDROCHLORIDE are not available; however, TRIPELENNAMINE HYDROCHLORIDE is probably combustible.
TRIPELENNAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21663 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29899 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49403 | 58 | Inquiry |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-15319487004 | China | 2132 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
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