Sulfaguanidine
- CAS No.
- 57-67-0
- Chemical Name:
- Sulfaguanidine
- Synonyms
- SG;SULPHAGUANIDINE;4-amino-N-carbamimidoylbenzenesulfonamide;SULFAQUANIDINE;Sulfoguanidine;50DAG;A-307;Diacta;Sulgin;rp2275
- CBNumber:
- CB7152799
- Molecular Formula:
- C7H10N4O2S
- Molecular Weight:
- 214.24
- MOL File:
- 57-67-0.mol
- Modify Date:
- 2024/4/25 13:42:50
| Melting point | 190-193°C |
|---|---|
| Boiling point | 426.1±47.0 °C(Predicted) |
| Density | 1.3916 (rough estimate) |
| refractive index | 1.6440 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | 1 M HCl: soluble50mg/mL |
| form | Powder |
| pka | pKa 2.37(H2O t = 37) (Uncertain) |
| color | white to off-white |
| Water Solubility | 1g/1000mL at 25 ºC |
| Merck | 14,8908 |
| BRN | 2695326 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 57-67-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Sulfaguanidine(57-67-0) |
| EPA Substance Registry System | Benzenesulfonamide, 4-amino-N-(aminoiminomethyl)- (57-67-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | WO8575000 | |||||||||
| F | 10 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29350090 | |||||||||
| NFPA 704 |
|
Sulfaguanidine price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S8751 | Sulfaguanidine | 57-67-0 | 25G | ₹2749.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S8751 | Sulfaguanidine | 57-67-0 | 100G | ₹4806.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S8751 | Sulfaguanidine | 57-67-0 | 500G | ₹11052.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 32402 | Sulfaguanidine VETRANAL?, analytical standard | 57-67-0 | 100MG | ₹6657.38 | 2022-06-14 | Buy |
| TCI Chemicals (India) | S0464 | Sulfaguanidine | 57-67-0 | 25G | ₹2100 | 2022-05-26 | Buy |
Sulfaguanidine Chemical Properties,Uses,Production
Chemical Properties
white powder
Uses
Sulfaguanidine is a sulfonamide based antibiotic drug with potential application in veterinary medicine.
World Health Organization (WHO)
Sulfaguanidine, a sulfonamide anti-infective agent, was introduced in 1941 for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing bacterial resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Although sulfaguanidine, which is poorly absorbed from the gastrointestinal tract, is no longer recommended in some countries, it continues to be used in others for the treatment of local intestinal infections, including bacterial dysentery, and for preoperative bowel preparation.
Pharmaceutical Applications
1-Sulfanilylguanidine. A poorly absorbed compound, less potent than succinylsulfathiazole but with similar uses. Blood concentrations of 15–40 mg/L have been found after single doses of 1–7 g. Excretion in the urine is rapid.
Safety Profile
Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. See also SULFONATES. When heated to decomposition it emits very toxic fumes of SO, and NO,.
Purification Methods
Crystallise the antibacterial from hot water (7mL/g). [Beilstein 14 III 1970, 14 IV 2668.]
Sulfaguanidine Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Orgamine Chemicals(I) Pvt Ltd | +91-9820080281 +91-9820080281 | Maharashtra, India | 451 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Anant Pharmaceuticals Pvt. ltd | +91 8550986868 | Maharashtra, India | 736 | 58 | Inquiry |
| Nakshatra Chemicals | 09819631316 | Mumbai, India | 162 | 58 | Inquiry |
| Sign Pharma Trade Services Pvt., Ltd.(SPTS) | 91-22-23481235 | Mumbai, India | 160 | 58 | Inquiry |
| Global Chem Asia Pacific | 91-9849161572 | Hyderabad, India | 255 | 58 | Inquiry |
| Unitrade Agencies | 08048372548Ext 632 | Mumbai, India | 197 | 58 | Inquiry |
| Vyshno Bio Sciences | 91-7095439993 | Hyderabad, India | 239 | 58 | Inquiry |
| Anant Pharmaceuticals Pvt., Ltd. | 91-9324977784 | Maharashtra, India | 160 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |