ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Metabolism >Carbonic Anhydrase Inhibitors >Dorzolamide Hydrochloride
Dorzolamide Hydrochloride
- CAS No.
- 130693-82-2
- Chemical Name:
- Dorzolamide Hydrochloride
- Synonyms
- MK 507;mk-0507;Trusopt;Biosopt;CS-1398;L 671152;Dorzalamide;DORZOLAMIDE HCL;Dorzolamide HCI;TRUSOPT; COSOPT
- CBNumber:
- CB7296763
- Molecular Formula:
- C10H17ClN2O4S3
- Molecular Weight:
- 360.9
- MOL File:
- 130693-82-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:16
| Melting point | 265-2670C |
|---|---|
| alpha | D24 -8.34° (c = 1 in methanol) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Soluble in water, slightly soluble in methanol, very slightly soluble in anhydrous ethanol. |
| form | Solid |
| color | White to Off-White |
| λmax | 254nm(CHCl3:MeOH= aq.)(lit.) |
| Merck | 14,3426 |
| BRN | 5896026 |
| CAS DataBase Reference | 130693-82-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H373 | |||||||||
| Precautionary statements | P260-P264-P270-P301+P312-P314-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XJ9095163 | |||||||||
| HS Code | 2935904000 | |||||||||
| NFPA 704 |
|
Dorzolamide Hydrochloride price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR1925 | Dorzolamide hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 130693-82-2 | 500MG | ₹27776.95 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D4189 | Dorzolamide Hydrochloride | 130693-82-2 | 200MG | ₹8800 | 2022-05-26 | Buy |
Dorzolamide Hydrochloride Chemical Properties,Uses,Production
Description
Dorzolamide hydrochloride was introduced in the U.S.A. as eye drops for the treatment of open-angle glaucoma and ocular hypertension. Dorzolamide is a potent carbonic anhydrase inhibitor that, on topical administration, lowers intraocular pressure (IOP). In a clinical study in patients with bilateral primary open-angle glaucoma or ocular hypertension, dorzolamide (0.7-2%) was found to significantly lower IOP throughout the day. Dorzolamide has been shown to be effective as a single therapy or in combination with β-blockers.
Chemical Properties
White Powder
Uses
Carbonic anhydrase inhibitor. Antiglaucoma agent.
Definition
ChEBI: The hydrochloride salt of dorzolamide. It is used in ophthalmic solutions to lower increased intraocular pressure in the treatment of open-angle glaucoma and ocular hypertension.
Dorzolamide Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 433)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Siddhivinayakchemicals | +91-912225190111 +91-9819773074 | Mumbai, India | 42 | 58 | Inquiry |
| Flax Laboratories | +91-9867665132 +91-9867665132 | Maharashtra, India | 44 | 58 | Inquiry |
| SHOBHA LIFE SCIENCES PRIVATE LIMITED | +919121212469 | Hyderabad, India | 31 | 58 | Inquiry |
| KARPSCHEM LABORATORIES | +91-7249203006 +91-7249203006 | Maharashtra, India | 786 | 58 | Inquiry |
| FDC Limited | +912226782653 | Mumbai, India | 30 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Precise Biopharma Pvt Ltd | +91-2267828600 +91-2267828600 | Maharashtra, India | 46 | 58 | Inquiry |
| Lake Chemicals Pvt Ltd | 91-80-22868600 | Karnataka, India | 9 | 58 | Inquiry |
| Indoco Remedies Ltd | +91-2262871000 +91-2262871000 | Gujarat, India | 27 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Jigs Chemical ltd | 58 |
| Siddhivinayakchemicals | 58 |
| Flax Laboratories | 58 |
| SHOBHA LIFE SCIENCES PRIVATE LIMITED | 58 |
| KARPSCHEM LABORATORIES | 58 |
| FDC Limited | 58 |
| Hetero Drugs Limited | 58 |
| Precise Biopharma Pvt Ltd | 58 |
| Lake Chemicals Pvt Ltd | 58 |
| Indoco Remedies Ltd | 58 |
130693-82-2(Dorzolamide Hydrochloride)Related Search:
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3-b)thiopyran-2-sulfonamide,5,6-dihydro-4-(ethylamino)-6-methyl-4h-thieno(
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DORZOLAMIDE HYDROCHLORIDE
dorzolomide hydrochloride
DorzolomideHcl,Usp
Dorzolamide HCI
4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,
6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S,6S) DORZOLAMIDEHYDROCHLORIDE(SUBJECTTOPATENTFREE) (S,S)-(-)-5,6-Dihydro-4-ethylamino-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide monohydrochloride 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S,6S)- 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S-trans)- L 671152 MK 507 Trusopt Biosopt Dorzalamide (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Hydrochloride (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-β]thiopyran-2-sulfonamide 7,7-Dioxide Hydrochloride DorzolaMide Hydrochloride, USP Dorzolamide Hydrochloride (200 mg) Dorzolamide Hydrochloride USP/EP/BP Dorzolamide HydrochlorideQ: What is Dorzolamide Hydrochloride Q: What is the CAS Number of Dorzolamide Hydrochloride Q: What is the storage condition of Dorzolamide Hydrochloride Q: What are the applications of Dorzolamide Hydrochloride Dorzolamide Hydrochloride (1225281) (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride Dorzolamide For System Suitability EPCR CS-1398 TRUSOPT; COSOPT 4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide hydrochloride Dorzolamide hydrochloride CRS Dorzolamide Hydrochloride RS Dorzolamide for system suitability CRS DorzolamideHydrochloride> Dorzolomide hcl Dorzolamide/L671152/MK507 (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b] thiopyran-2-sulphonamide 7,7-dioxide hydrochloride. Dorzolamide (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3- b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride 130693-82-2 30693-82-2 C10H17ClN2O4S3 C10H16N2O4S3ClH C10H16N2O4S3HCl Inhibitors Heterocycles Sulfur & Selenium Compounds Chiral Reagents Intermediates & Fine Chemicals
6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S,6S) DORZOLAMIDEHYDROCHLORIDE(SUBJECTTOPATENTFREE) (S,S)-(-)-5,6-Dihydro-4-ethylamino-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide monohydrochloride 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S,6S)- 4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, monohydrochloride, (4S-trans)- L 671152 MK 507 Trusopt Biosopt Dorzalamide (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-Dioxide Hydrochloride (4S,6S)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-β]thiopyran-2-sulfonamide 7,7-Dioxide Hydrochloride DorzolaMide Hydrochloride, USP Dorzolamide Hydrochloride (200 mg) Dorzolamide Hydrochloride USP/EP/BP Dorzolamide HydrochlorideQ: What is Dorzolamide Hydrochloride Q: What is the CAS Number of Dorzolamide Hydrochloride Q: What is the storage condition of Dorzolamide Hydrochloride Q: What are the applications of Dorzolamide Hydrochloride Dorzolamide Hydrochloride (1225281) (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride Dorzolamide For System Suitability EPCR CS-1398 TRUSOPT; COSOPT 4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide hydrochloride Dorzolamide hydrochloride CRS Dorzolamide Hydrochloride RS Dorzolamide for system suitability CRS DorzolamideHydrochloride> Dorzolomide hcl Dorzolamide/L671152/MK507 (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b] thiopyran-2-sulphonamide 7,7-dioxide hydrochloride. Dorzolamide (4S,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3- b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride 130693-82-2 30693-82-2 C10H17ClN2O4S3 C10H16N2O4S3ClH C10H16N2O4S3HCl Inhibitors Heterocycles Sulfur & Selenium Compounds Chiral Reagents Intermediates & Fine Chemicals