Warfarin sodium
![Warfarin sodium Structure](CAS/GIF/129-06-6.gif)
- CAS No.
- 129-06-6
- Chemical Name:
- Warfarin sodium
- Synonyms
- VITAMIN K2;athrombin;panwarfin;WARFARIN SODIUM SALT;3-(ALPHA-ACETONYLBENZYL)-4-HYDROXYCOUMARIN;SODIUM 4-OXO-3-(3-OXO-1-PHENYL-BUTYL)-CHROMEN-2-OLATE;waran;varfine;marevan;tintorane
- CBNumber:
- CB7346095
- Molecular Formula:
- C19H15O4.Na
- Molecular Weight:
- 330.31
- MOL File:
- 129-06-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/10 11:19:08
Melting point | approximate 161℃ |
---|---|
alpha | ±0° |
storage temp. | 2-8°C |
solubility | Very soluble in water and in ethanol (96 per cent), soluble in acetone, very slightly soluble in methylene chloride. |
color | White to Almost white |
PH | pH (10g/l, 25℃) : 7.2~8.3 |
Merck | 14,10038 |
BCS Class | 1,2 |
CAS DataBase Reference | 129-06-6(CAS DataBase Reference) |
EPA Substance Registry System | Sodium warfarin (129-06-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS06,GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H300-H360-H412 | |||||||||
Precautionary statements | P202-P264-P270-P273-P280-P301+P310 | |||||||||
Hazard Codes | T+ | |||||||||
Risk Statements | 61-28 | |||||||||
Safety Statements | 53-36/37/39-45-36/37-28 | |||||||||
RIDADR | UN 1544 6.1/PG 2 | |||||||||
WGK Germany | 1 | |||||||||
RTECS | GN4725000 | |||||||||
HazardClass | 6.1(a) | |||||||||
PackingGroup | II | |||||||||
HS Code | 29322090 | |||||||||
Toxicity | LD50 in male rats, female rats, mice, rabbits (mg/kg): 323, 58, 374, ~800 orally (Hagen); also reported as LD50 in male, female rats (mg/kg): 100.3, 8.7 orally (Back) | |||||||||
NFPA 704 |
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Warfarin sodium price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A4571 | 3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium salt ≥98% | 129-06-6 | 10G | ₹9157.95 | 2022-06-14 | Buy |
TCI Chemicals (India) | W0005 | Warfarin Sodium (contains Isopropyl Alcohol) | 129-06-6 | 5G | ₹4700 | 2022-05-26 | Buy |
TCI Chemicals (India) | W0005 | Warfarin Sodium (contains Isopropyl Alcohol) | 129-06-6 | 25G | ₹10000 | 2022-05-26 | Buy |
Warfarin sodium Chemical Properties,Uses,Production
Chemical Properties
Colorless solid
Uses
Warfarin Sodium (Crystalline Clathrate) is used for pharmaceutical care for patients with chronic heart failure and renal dysfunction.
General Description
Slightly bitter crystalline powder. An anticoagulant used as a rodenticide.
Reactivity Profile
A coumarin derivative, a lactone. Lactones are similar to esters reactive chemistries.
Health Hazard
Warfarin sodium is highly toxic orally in humans.
Fire Hazard
When heated to decomposition, Warfarin sodium emits toxic fumes of sodium oxide.
Clinical Use
By virtue of its great potency, warfarin sodium at firstwas considered unsafe for use in humans and was used veryeffectively as a rodenticide, especially against rats. At theproper dosage level, however, it can be used in humans, especiallythrough the intravenous route.
Safety Profile
Poison to humans by ingestion. Experimental poison by ingestion and intravenous routes. Human systemic effects by ingestion: dermatitis. Human reproductive effects by ingestion: fetotoxicity, abnormal condition of newborn at birth, other newborn physical effects, and teratogenic effects includmg developmental abnormalities of the eye and ear, craniofacial area, skin and appendages, musculoskeletal system, cardiovascular system, and gastrointestinal system of the fetus. ,4n experimental teratogen. Other experimental reproductive effects. Mutation data reported. An anticoagulant drug. When heated to decomposition it emits toxic fumes of Na2O.
Warfarin sodium Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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SNECOFRi Pvt Ltd | +91-9032850129 +91-9032850129 | Telangana, India | 404 | 58 | Inquiry |
Alembic Pharmaceuticals Limited | +91-2652280880 +91-2652280550 | Gujarat, India | 115 | 58 | Inquiry |
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VIVIN DRUGS AND PHARMACEUTICALS LTD | +91-22670456625 +91-224067045635 | Telangana, India | 22 | 58 | Inquiry |
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Venkata Narayana Active Ingredients Pvt Ltd | +91-9940284484 +91-9840119000 | Tamil Nadu, India | 22 | 58 | Inquiry |
SP Accure Labs Pvt Ltd (SPAL) | +91-8418663201 +91-8418663201 | Telangana, India | 4 | 58 | Inquiry |
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