ChemicalBook > Product Catalog >Flavors and fragrances >Synthetic fragrances >Oxygen-containing heterocyclic compounds >Thiazole, thiophene, and pyridine >(R)-3-Hydroxypyrrolidine
(R)-3-Hydroxypyrrolidine
- CAS No.
- 2799-21-5
- Chemical Name:
- (R)-3-Hydroxypyrrolidine
- Synonyms
- (R)-PYRROLIDIN-3-OL;(3R)-Pyrrolidin-3-ol;R-HP;98%，ee99%;(R)-3-PYRROLIDINOL;(-)-3-Pyrrolidinol;(3R)-3-PYRROLIDINOL;3-PYRROLIDINOL, (R);(R)-Pyrrolidine-3-ol;R-(-)-3-PYRROLIDINOL
- CBNumber:
- CB7494161
- Molecular Formula:
- C4H9NO
- Molecular Weight:
- 87.12
- MOL File:
- 2799-21-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/4 20:04:50
| Melting point | 15°C |
|---|---|
| Boiling point | 215-216 °C (lit.) |
| alpha | 6.5 º (c=3.5% in MeOH) |
| Density | 1.078 g/mL at 20 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 14.91±0.20(Predicted) |
| form | Viscous Liquid |
| color | Clear yellow to orange-brown |
| Specific Gravity | 1.048 |
| optical activity | [α]20/D +6.5°, c = 3.5 in methanol |
| Water Solubility | Soluble in water and methanol. |
| Sensitive | Air Sensitive & Hygroscopic |
| BRN | 5376132 |
| CAS DataBase Reference | 2799-21-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280a-P321-P332+P313-P337+P313-P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-34 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
(R)-3-Hydroxypyrrolidine price More Price(2)
(R)-3-Hydroxypyrrolidine Chemical Properties,Uses,Production
Chemical Properties
clear yellow to orange-brown viscous liquid
Uses
(R)-Pyrrolidin-3-ol is used in preparation of allosteric BCR-ABL bifunctional proteolysis targeting chimera compounds.
Purification Methods
The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]
(R)-3-Hydroxypyrrolidine Preparation Products And Raw materials
Raw materials
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Global( 307)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BTC pharm India | +918790379245 | AndhraPradesh, India | 1262 | 58 | Inquiry |
| BTC pharm India | +918790379245 | Telangana, India | 143 | 58 | Inquiry |
| ARRKEM LIFE SCIENCES PRIVATE LIMITED | +91-8148739767 +91-8148739767 | Telangana, India | 347 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | China | 18154 | 58 | Inquiry |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | China | 10986 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20287 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | China | 29791 | 60 | Inquiry |
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(R)-3-Pyrrolidinol>
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(R)-PYRROLIDIN-3-OL
(-)-3-Pyrrolidinol
2799-21-5
Asymmetric Synthesis
Simple Alcohols (Chiral)
Chiral Building Blocks
Heterocyclic Building Blocks
Pyrrolidines
pharmacetical
API intermediates
Chiral Building Blocks
Simple Alcohols (Chiral)
Synthetic Organic Chemistry