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GO 6983

GO 6983 Structure
CAS No.
133053-19-7
Chemical Name:
GO 6983
Synonyms
CS-674;gǒ 6983;Gδ 6983;GOE 6983;Go6983(96 %);GO6983 GO-6983;GO 6983 USP/EP/BP;G 6983 - GO 6983 | Goe 6983;GOE 6983;GO6983 GO-6983;GO 6983;G 6983 - CAS 133053-19-7 - Calbiochem
CBNumber:
CB7498134
Molecular Formula:
C26H26N4O3
Molecular Weight:
442.51
MOL File:
133053-19-7.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

GO 6983 Properties

Boiling point 709.0±60.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: 20 mg/mL, clear, red
form powder
pka 8.02±0.60(Predicted)
color red
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  2933998090
NFPA 704
0
2 0

GO 6983 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) G1918 Gö 6983 ≥97% 133053-19-7 500μG ₹11463.68 2022-06-14 Buy
Sigma-Aldrich(India) G1918 Gö 6983 ≥97% 133053-19-7 1MG ₹21974.75 2022-06-14 Buy
Sigma-Aldrich(India) 365251 Gö 6983 - CAS 133053-19-7 - Calbiochem A potent, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (PKC) that inhibits several PKC isozymes. 133053-19-7 500μG ₹15469.99 2022-06-14 Buy
Product number Packaging Price Buy
G1918 500μG ₹11463.68 Buy
G1918 1MG ₹21974.75 Buy
365251 500μG ₹15469.99 Buy

GO 6983 Chemical Properties,Uses,Production

Uses

Go 6983, is a protein kinase C (PKC) inhibitor.Potent PKC Inhibitor

Biological Activity

Broad spectrum protein kinase C (PKC) inhibitor (IC 50 values are 7, 7, 6, 10, 60 and 20000 nM for PKC α , PKC β , PKC γ , PKC δ , PKC ζ and PKC μ respectively). Displays cardioprotective properties; reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.

Biochem/physiol Actions

Protein kinase C (PKC) inhibitor that selectively inhibits several PKC isozymes (IC50 = 7 nM for PKCα and PKCβ; 6 nM for PKCγ; 10 nM for PKCδ; and 60 nM for PKCζ), but does not inhibit PKCμ (IC50 = 20 mM).

GO 6983 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 113)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26216 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry

GO 6983 Spectrum

gǒ 6983 GOE 6983 Gδ 6983 1H-Pyrrole-2,5-dione, 3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)- Go6983(96 %) G 6983 - GO 6983 | Goe 6983 CS-674 G 6983 - CAS 133053-19-7 - Calbiochem GO6983 GO-6983 GOE 6983;GO6983 GO-6983;GO 6983 3-[1-(3-Dimethylamino-propyl)-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-pyrrole-2,5-dione GO 6983 USP/EP/BP 133053-19-7 Smad TGF-beta Inhibitors TGF-beta/Smad