ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >TGF-beta / Smad >PKC inhibitor >GO 6983
GO 6983
![GO 6983 Structure](CAS/GIF/133053-19-7.gif)
- CAS No.
- 133053-19-7
- Chemical Name:
- GO 6983
- Synonyms
- CS-674;gǒ 6983;Gδ 6983;GOE 6983;Go6983(96 %);GO6983 GO-6983;GO 6983 USP/EP/BP;G 6983 - GO 6983 | Goe 6983;GOE 6983;GO6983 GO-6983;GO 6983;G 6983 - CAS 133053-19-7 - Calbiochem
- CBNumber:
- CB7498134
- Molecular Formula:
- C26H26N4O3
- Molecular Weight:
- 442.51
- MOL File:
- 133053-19-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
Boiling point | 709.0±60.0 °C(Predicted) |
---|---|
Density | 1.31±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMSO: 20 mg/mL, clear, red |
form | powder |
pka | 8.02±0.60(Predicted) |
color | red |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
HS Code | 2933998090 | |||||||||
NFPA 704 |
|
GO 6983 price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | G1918 | Gö 6983 ≥97% | 133053-19-7 | 500μG | ₹11463.68 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | G1918 | Gö 6983 ≥97% | 133053-19-7 | 1MG | ₹21974.75 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 365251 | Gö 6983 - CAS 133053-19-7 - Calbiochem A potent, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (PKC) that inhibits several PKC isozymes. | 133053-19-7 | 500μG | ₹15469.99 | 2022-06-14 | Buy |
GO 6983 Chemical Properties,Uses,Production
Uses
Go 6983, is a protein kinase C (PKC) inhibitor.Potent PKC Inhibitor
Biological Activity
Broad spectrum protein kinase C (PKC) inhibitor (IC 50 values are 7, 7, 6, 10, 60 and 20000 nM for PKC α , PKC β , PKC γ , PKC δ , PKC ζ and PKC μ respectively). Displays cardioprotective properties; reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
Biochem/physiol Actions
Protein kinase C (PKC) inhibitor that selectively inhibits several PKC isozymes (IC50 = 7 nM for PKCα and PKCβ; 6 nM for PKCγ; 10 nM for PKCδ; and 60 nM for PKCζ), but does not inhibit PKCμ (IC50 = 20 mM).
GO 6983 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 113)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | China | 8474 | 58 | Inquiry |
133053-19-7(GO 6983)Related Search:
gǒ 6983
GOE 6983
Gδ 6983
1H-Pyrrole-2,5-dione, 3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-
Go6983(96 %)
G 6983 - GO 6983 | Goe 6983
CS-674
G 6983 - CAS 133053-19-7 - Calbiochem
GO6983 GO-6983
GOE 6983;GO6983 GO-6983;GO 6983
3-[1-(3-Dimethylamino-propyl)-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-pyrrole-2,5-dione
GO 6983 USP/EP/BP
133053-19-7
Smad
TGF-beta
Inhibitors
TGF-beta/Smad