Ethyl N-(4-methylphenyl)sulfonylcarbamate

Ethyl N-(4-methylphenyl)sulfonylcarbamate Structure
CAS No.
5577-13-9
Chemical Name:
Ethyl N-(4-methylphenyl)sulfonylcarbamate
Synonyms
Tosylurethane;ethyl tosylcarbaMate;Gliclazide IMpurity C;Gliclazide EP Impurity C;Tosylcarbamic acid ethyl ester;Ethyl [(4-Methylphenyl)sulphonyl]ca;ethyl n-(4-methylphenyl)sulfonylcarbamate;Ethyl [(4-methylphenyl)sulfonyl]-carbamate;Ethyl [(4-methylphenyl)sulphonyl]carbamate;Ethyl N-(4-methylbenzenesulfonyl)carbamate
CBNumber:
CB7512137
Molecular Formula:
C10H13NO4S
Molecular Weight:
243.28
MOL File:
5577-13-9.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

Ethyl N-(4-methylphenyl)sulfonylcarbamate Properties

Melting point 82-84oC
Boiling point 272℃ at 100.8-101kPa
Density 1.38 at 20℃
vapor pressure 1.8-7.9Pa at 20-25℃
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Solid
color White
LogP 0.73-1.7 at 23℃ and pH2-7
Surface tension 63.8mN/m at 1g/L and 20℃

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Ethyl N-(4-methylphenyl)sulfonylcarbamate Chemical Properties,Uses,Production

Uses

Tosylurethane (Gliclazide EP Impurity C) is an intermediate in the synthesis of Gliclazide (G409877), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.

Ethyl N-(4-methylphenyl)sulfonylcarbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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ethyl n-(4-methylphenyl)sulfonylcarbamate Ethyl [(4-methylphenyl)sulphonyl]carbamate N-(p-Tolylsulfonyl)carbamic acid ethyl ester Tosylcarbamic acid ethyl ester N-(4-methylphenyl)sulfonylcarbamic acid ethyl ester ethyl tosylcarbaMate Gliclazide IMpurity C Tosylurethane 3-ethyl-4-methylbenzenesulfonic acid carbamoyl ester Gliclazide EP Impurity C Ethyl [(4-methylphenyl)sulfonyl]-carbamate Gliclazide Impurity 3(Gliclazide EP Impurity C) Ethyl [(4-Methylphenyl)sulphonyl]ca Carbamic acid, N-[(4-methylphenyl)sulfonyl]-, ethyl ester Ethyl N-(4-methylbenzenesulfonyl)carbamate Gliclazide EP Impurity C Gliclazide BP Impurity C 5577-13-9