ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Hydroxypyridine >E 7010
E 7010
- CAS No.
- 141430-65-1
- Chemical Name:
- E 7010
- Synonyms
- E 7010;CS-505;CS-1806;ABT-751 (E;E7010(ABT-751);ABT-751 ABT751;ABT-751 (E7010);E 7010 ISO 9001：2015 REACH;ABT-751 (E7010);ABT751; ABT 751;ABT751; ABT 751; E7010; E-7010; E 7010
- CBNumber:
- CB81367030
- Molecular Formula:
- C18H17N3O4S
- Molecular Weight:
- 371.41
- MOL File:
- 141430-65-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:36
| Melting point | 162 °C(dec.) |
|---|---|
| Boiling point | 551.0±60.0 °C(Predicted) |
| Density | 1.427 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥25.53 mg/mL in EtOH with ultrasonic |
| form | powder to crystal |
| pka | 7.86±0.40(Predicted) |
| color | White to Yellow to Orange |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H361-H302-H373 | |||||||||
| Precautionary statements | P260-P314-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501 | |||||||||
| RTECS | DB2734000 | |||||||||
| HS Code | 2935.90.9500 | |||||||||
| NFPA 704 |
|
E 7010 price More Price(2)
E 7010 Chemical Properties,Uses,Production
Description
ABT-751 is a tubulin polymerization inhibitor that binds to the colchicine binding site on β-tubulin (Ki = 3.3 μM). It inhibits tubulin polymerization in a concentration-dependent manner and inhibits growth of 26 human tumor cell lines (IC50s = 0.06-0.08 μg/ml). ABT-751 (100 mg/kg, p.o.) induces tumor regression in NB-1382 neuroblastoma, IRS56 rhabdomyosarcoma, and KT-6 Wilms mouse xenograft models. It also induces tumor endothelial cell retraction and reduces tumor perfusion, but not muscle perfusion, in a 9L rat glioma subcutaneous tumor model.
E 7010 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 130)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 18623 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32835 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29899 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49403 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23555 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 23499 | 58 | Inquiry |
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E 7010
N-[2-(4-HYDROXYANILINO)PYRIDIN-3-YL]-4-METHOXYBENZENE-1-SULFONAMIDE
N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide
BenzenesulfonaMide, N-[2-[(4-hydroxyphenyl)aMino]-3-pyridinyl]-4-Methoxy-
ABT-751 (E7010)
N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide
ABT-751 (E
E7010(ABT-751)
ABT-751 (E7010);ABT751; ABT 751
CS-1806
ABT751; ABT 751; E7010; E-7010; E 7010
N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide
CS-505
E 7010 ISO 9001：2015 REACH
ABT-751 ABT751
Microtubule/Tubulin,E 7010,Autophagy,E-7010,Inhibitor,inhibit,ABT 751,ABT751,ABT-751
141430-65-1
Inhibitors