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SB 242084 (hydrochloride)

SB 242084 (hydrochloride) Structure
CAS No.
1049747-87-6
Chemical Name:
SB 242084 (hydrochloride)
Synonyms
SB 242084 2HCL;CAS 1049747-87-6;SB-242084 HCl salt;SB 242084 (hydrochloride);SB242084;SB 242084;CAS 1049747-87-6
CBNumber:
CB82592406
Molecular Formula:
C21H21Cl3N4O2
Molecular Weight:
467.77604
MOL File:
1049747-87-6.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:20
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SB 242084 (hydrochloride) Properties

storage temp. Sealed in dry,Room Temperature
solubility Ethanol:1.0(Max Conc. mg/mL);2.14(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);21.38(Max Conc. mM)
DMSO:59.63(Max Conc. mg/mL);127.47(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);64.13(Max Conc. mM)
form A crystalline solid
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

SB 242084 (hydrochloride) Chemical Properties,Uses,Production

Description

Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that activates specific receptors located primarily in the gut and central nervous system. SB-242084 is an antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold more selectivity over other 5-HT, dopamine, or adrenergic receptors. In vivo, it is brain penetrant and has significant anxiolytic activity, without sedative, proconvulsant, or hyperphagic properties. SB-242084 has been used extensively in animal research to evaluate, for example, 5-HT2C receptor agonists and neurotransmitter receptor interactions in mice.

Uses

SB 242084 Hydrochloride is an antagonist of the SR-2C.

SB 242084 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

SB 242084 (hydrochloride) Suppliers

Global( 60)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai Chaoyan Biotechnology Co., Ltd. 021-50840550 CHINA 6217 58 Inquiry
Shanghai Hao Biological Technology Co., Ltd. 021-58116080 18019263206 CHINA 6921 58 Inquiry
Shanghai Jijin Chemical Technology Co., Ltd. 400-002-6926 15900443528 CHINA 6617 58 Inquiry
Shenzhen Xinbosheng Biological Technology Co., Ltd. 0755-26755892 CHINA 6164 58 Inquiry
Supplier Advantage
A.J Chemicals 58
InvivoChem 58
Nantong HI-FUTURE Biology Co., Ltd. 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58
Shanghai Chaoyan Biotechnology Co., Ltd. 58
Shanghai Hao Biological Technology Co., Ltd. 58
Shanghai Jijin Chemical Technology Co., Ltd. 58
Shenzhen Xinbosheng Biological Technology Co., Ltd. 58

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SB 242084 (hydrochloride) SB-242084 HCl salt CAS 1049747-87-6 SB242084;SB 242084;CAS 1049747-87-6 SB 242084 2HCL 1049747-87-6 C21H19ClN4O22ClHH2O API