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Methyl 2-phenylacetoacetate

Methyl 2-phenylacetoacetate Structure
CAS No.
16648-44-5
Chemical Name:
Methyl 2-phenylacetoacetate
Synonyms
BMK Glycidate;Benzeneacetic;Methyl 3-oxo-2-phenylbutanoate;BMK glycidate oil;Benzeneacetic acid, a-acetyl-, methyl ester;PBMK;BMK PRICE;bmk factory;bmk white powder;BMK CHINA FACTORY
CBNumber:
CB83067497
Molecular Formula:
C11H12O3
Molecular Weight:
192.21
MOL File:
16648-44-5.mol
MSDS File:
SDS
Modify Date:
2023/5/9 9:30:52

Methyl 2-phenylacetoacetate Properties

Melting point 58.5-59.0 °C
Boiling point 92-96 °C(Press: 0.6 Torr)
Density 1?+-.0.06 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMSO: 50 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 50 mg/ml; Methanol: 1 mg/ml
form A crystalline solid
pka 10.67±0.46(Predicted)

Methyl 2-phenylacetoacetate Chemical Properties,Uses,Production

Description

Methyl 2-phenylacetoacetate (Item No. 28352) is an analytical reference standard categorized as a precursor in the synthesis of amphetamines and methamphetamines. This product is intended for research and forensic applications.

Uses

D1, D2 dopamine receptor antagonist; butyrophenone antipsychotic and anti-emetic. Droperidol is a potent antagonist of dopamine subtype 2 receptor. It is an antipsychotic, which is used to treat acute behavioral anomalies. It helps to manage postoperative nausea and vomiting. Endogenous κ1b opioid receptor agonist.

Preparation

Methyl phenyldiazoacetate, precursor to cyclopropanation agents, is prepared by treating methyl phenylacetate with p-acetamidobenzenesulfonyl azide in the presence of base.

Methyl 2-phenylacetoacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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