Bitertanol
![Bitertanol Structure](CAS/GIF/55179-31-2.gif)
- CAS No.
- 55179-31-2
- Chemical Name:
- Bitertanol
- Synonyms
- BAYCOR;kwg0599;SIBUTOL;R 33986;Baycoral;(1RS,2RS;Biloxuron;biloxazol;BAYMAT(R);AI3-27699
- CBNumber:
- CB8442457
- Molecular Formula:
- C20H23N3O2
- Molecular Weight:
- 337.42
- MOL File:
- 55179-31-2.mol
- Modify Date:
- 2024/8/13 12:20:35
Melting point | 49-50°C |
---|---|
Boiling point | 350°C |
Density | 1.1676 (rough estimate) |
vapor pressure | A 2.2 x l0-10 (20 °C) B 2.5 x l0-9 (20 °C) |
refractive index | 1.6200 (estimate) |
Flash point | 100 °C |
solubility | Chloroform: slightl soluble,DMSO: Slightly Soluble,Methanol: Slightly Soluble |
Water Solubility | A 2.7 mg l-1 (20 °C) B 1.1 mg l-1 (20 °C) |
pka | 13.40±0.20(Predicted) |
Merck | 13,1301 |
BRN | 620948 |
NIST Chemistry Reference | 1H-1,2,4-triazole-1-ethanol, «beta»-([1,1'-biphenyl]-4-yloxy)-«alpha»-(1,1-dimethylethyl)-(55179-31-2) |
EPA Substance Registry System | Bitertanol (55179-31-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
Hazard Codes | T | |||||||||
Risk Statements | 22-23 | |||||||||
Safety Statements | 45 | |||||||||
RIDADR | UN 2811 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | XZ4803050 | |||||||||
Toxicity | LD50 in rats, male and female mice (mg/kg): >5000, 4488, 4202 orally (Brandes) | |||||||||
NFPA 704 |
|
Bitertanol Chemical Properties,Uses,Production
Description
Bitertanol is a broad-spectrum triazole fungicide that is active against a variety of fungi, including V. inaequalis and V. pirina, which are responsible for apple and pear scab, respectively, as well as S. mors-uvae and P. ribis, which are responsible for American gooseberry mildew and leaf spot in black currants, respectively. It is active against isolates of V. inaequalis (MICs = 0.6 and 1 μg/ml) but repeated use leads to resistance and cross-resistance (MICs = 9.8-13 μg/ml for bitertanol-resistant isolates). Bitertanol inhibits the cytochrome P450 (CYP450) isoform CYP3A4 (IC50 = 2.74 μM) and inhibits androgenic activity induced by the androgen receptor agonist DHT in a yeast two-hybrid assay (IC50 = 79.85 μM). In rats, bitertanol (10-300 mg/kg, i.p.) increases operant responding on one- and five-minute fixed interval schedules with no effect on motor activity.
Chemical Properties
White Solid
Uses
Bitertanol is a foliar-applied triazole fungicide used to protect tropical and subtropical crops in agriculture, in particular bananas. Bitertanol has effects on behavior that are similar to those of psychomotor stimulants.
Agricultural Uses
Fungicide: A fungicide used to control a variety of diseases. Used as control for prunes when drying. Not currently registered in the U.S. or EU countries (pending). Used in many European, South American, Far Eastern and African countries, a well as in Australia for use on beans (all types) and various ornamentals. More than 20 global suppliers.
Trade name
BAYCOR®; BAY KWG 0599®; BAYMATSPRAY ®; BILOXAZOL®; KWG 0599®; SIBUTOL®, (with Fuberidazole)
Metabolic pathway
Bitertanol is a mixture of two diastereoisomeric pairs and this complicates its metabolism, each biotransfonnation affording a mixture of isomers. Metabolism has been studied under environmental conditions and in plants and mammals. Degradation in soil and sediments is slow and only small quantities of products (other than CO2 and bound residues) are produced. Most information is available for mammals in which metabolism occurs mainly by oxidative routes followed by conjugation. The information presented below is derived from the UK MAFF Pesticide Safety Directorate (PSD, 1994).
Bitertanol Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | China | 5867 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34571 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | China | 12272 | 58 | Inquiry |
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