Meclofenoxate hydrochloride
![Meclofenoxate hydrochloride Structure](CAS/GIF/3685-84-5.gif)
- CAS No.
- 3685-84-5
- Chemical Name:
- Meclofenoxate hydrochloride
- Synonyms
- CENTROPHENOXINE;MECLOFENOXATE HCL;CENTROPHENOXIN;mko;Cerut;acefen;brenal;cerutil;amipolen;marucotol
- CBNumber:
- CB9471047
- Molecular Formula:
- C12H16ClNO3.ClH
- Molecular Weight:
- 294.17
- MOL File:
- 3685-84-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/3/28 13:39:29
Melting point | 133-135°C |
---|---|
Density | 1.3255 (rough estimate) |
refractive index | 1.6140 (estimate) |
storage temp. | −20°C |
solubility | DMSO (Sparingly), Methanol (Slightly) |
form | Solid |
color | White to Off-White |
Merck | 14,5780 |
InChI | InChI=1S/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H |
InChIKey | FIVHOHCAXWQPGC-UHFFFAOYSA-N |
SMILES | C(OCCN(C)C)(=O)COC1=CC=C(Cl)C=C1.[H]Cl |
CAS DataBase Reference | 3685-84-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312a-P330-P501a | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
RTECS | AG0440000 | |||||||||
Toxicity | LD50 in mice (mg/kg): 330 i.v.; 1750 orally; 845 i.p. (Rumpf, Thuillier) | |||||||||
NFPA 704 |
|
Meclofenoxate hydrochloride Chemical Properties,Uses,Production
Description
Meclofenoxate hydrochloride is a cholinergic nootropic used as a dietary supplement and drug in the treatment of symptoms of senile dementia and Alzheimer's disease.
Chemical Properties
White Solid
Uses
Cerebral stimulant;Acetylcholine precursor
Mechanism of action
Meclofenoxate hydrochloride is a cholinergic drug that has been used to treat bowel diseases. It inhibits the enzyme acetylcholinesterase, which breaks down acetylcholine in the body and thus increases the amount of acetylcholine available to stimulate muscle contractions. Meclofenoxate hydrochloride also affects the production of other enzymes, such as those involved in energy metabolism.
Side effects
Possible side effects of meclofenoxate include insomnia, dizziness, restlessness, muscle tremors, depression, nausea, muscle tension, and headache, which are generally rare; these side effects may be associated with overdose of the medication and may indicate the need for a reduction in the dosage of the medication.
Safety Profile
Poison by intravenous route.Moderately toxic by ingestion and intraperitoneal routes.When heated to decomposition it emits very toxic fumes ofCl??, NOx, and HCl.
Meclofenoxate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics & Synthetics (P) Ltd. | 91-172-5066494 | Haryana, India | 631 | 58 | Inquiry |
Chengdu Aupone Pharmaceutical Co.Ltd. | +86-28-+86-28-87843998-6060-6060 +8618631098571 | China | 48 | 58 | Inquiry |
Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 | China | 887 | 58 | Inquiry |
Sigma Audley | +86-18336680971 +86-18126314766 | China | 496 | 58 | Inquiry |
Shanghai Aosiris new Material Technology Co., LTD | 86-15139564871 +8615139564871 | China | 264 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21673 | 55 | Inquiry |
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