2-Chlorobenzoyl chloride
- CAS No.
- 609-65-4
- Chemical Name:
- 2-Chlorobenzoyl chloride
- Synonyms
- O-CHLOROBENZOYL CHLORIDE;OCOC;o-ChL;SKL750;orobenzoyL;o-Chlorobenzoylchlor;chlorobenzoylchloride;o-Chlorbenzoylchlorid;o-Chlorobenzoylchlorid;LABOTEST-BB LTBB000568
- CBNumber:
- CB9721544
- Molecular Formula:
- C7H4Cl2O
- Molecular Weight:
- 175.01
- MOL File:
- 609-65-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/26 15:15:06
| Melting point | -4--3 °C (lit.) |
|---|---|
| Boiling point | 238 °C (lit.) |
| Density | 1.382 g/mL at 25 °C (lit.) |
| vapor pressure | 0.1 hPa (20 °C) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Store below +30°C. |
| form | Liquid |
| color | Clear colorless to very slightly yellow |
| explosive limit | 1.5-9.4%(V) |
| Water Solubility | Soluble in acetone, ether, and alcohol. Solubility in water it decomposes. |
| Sensitive | Moisture Sensitive |
| BRN | 386435 |
| CAS DataBase Reference | 609-65-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoyl chloride, 2-chloro-(609-65-4) |
| EPA Substance Registry System | Benzoyl chloride, 2-chloro- (609-65-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45-28A | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| F | 19-21 | |||||||||
| Autoignition Temperature | 600 °C | |||||||||
| Hazard Note | Corrosive/Moisture Sensitive | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29163900 | |||||||||
| Toxicity | LD50 orally in Rabbit: 3250 mg/kg | |||||||||
| NFPA 704 |
|
2-Chlorobenzoyl chloride price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 103918 | 2-Chlorobenzoyl chloride 95% | 609-65-4 | 5G | ₹881.16 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 103918 | 2-Chlorobenzoyl chloride 95% | 609-65-4 | 5G | ₹881.16 | 2022-06-14 | Buy |
| Sigma-Aldrich | 103918 | 2-Chlorobenzoyl chloride 95% | 609-65-4 | 100G | ₹3691.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 103918 | 2-Chlorobenzoyl chloride 95% | 609-65-4 | 100G | ₹3691.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.21989 | 2-Chlorobenzoyl chloride for synthesis | 609-65-4 | 250ML | ₹6730 | 2022-06-14 | Buy |
2-Chlorobenzoyl chloride Chemical Properties,Uses,Production
Chemical Properties
clear colourless to very slightly yellow liquid
Uses
2-Chlorobenzoyl chloride, is used in organic synthesis. It is used as a pharmaceutical intermediate for eg as an intermediate of clotrimazolc, preparation of p-chlorobenzoic acid and production of trichloro-acaricide.
Definition
ChEBI: An acyl chloride consisting of benzoyl chloride having a chloro substituent in the ortho-position.
General Description
2-Chlorobenzoyl chloride reacts with aromatic amines and ammonium thiocyanate using polyethylene glycol-400 as the catalyst under the condition of solid-liquid phase-transfer catalysis to form N-aryl-N′(2-chlorobenzoyl) thioureas. 2-Chlorobenzoyl chloride causes the acylation of polystyrene during the preparation and regeneration of the polystyrene-based resin.
Synthesis
A process for preparing 2-chlorobenzoyl chloride which comprises reacting 2-chlorobenzaldehyde with chlorine in the presence of phosphorus pentachloride at a temperature of from 50° to 200° C. and wherein the 2-chlorobenzaldehyde: phosphorus pentachloride ratio is from 1:0.05 to 1:0.2. Phosphorus pentachloride (41.5 g, 0.2 mole) was added to 2-chlorobenzaldehyde (289.7 g, 2.0 mole, 97%). After the ensuing exotherm had subsided, the resulting red solution was heated to 160° C. A stream of chlorine was introduced through a sparge tube into the solution for six hours. (Gas chromatography indicated 96.5% conversion.) The solution was then cooled and distilled under reduced pressure, giving 325.4 grams of 2-chlorobenzoyl chloride, which boiled at 135° to 140° C. at 16 millimeters of mercury. The yield of 2-Chlorobenzoyl chloride was 93% (98.5% pure).
2-Chlorobenzoyl chloride Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
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