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6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE

6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE

CAS:
545380-34-5
MF:
C22H20N4O
MW:
356.42

Properties

Melting point:
169-175°C
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO: soluble15mg/mL, clear
form 
powder
color 
white to beige
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS09
Signal word 
Warning
Hazard statements 
H302-H410
Precautionary statements 
P264-P270-P301+P312-P330-P501-P273-P391-P501
WGK Germany 
3

Use

QNZ is a novel inhibitor of NFkB which displays potent inhibitory effects on both NFKB transcriptional activation (IC50=11nM) and TNF-α production (IC50=7nM). It dose-dependently inhibited carragenin-induced edema formation in the rat paw model (1mg/Kg). A useful tool to explore the role of NFkB in cellular signaling pathways.

0 India supplier list of "6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE"

Sigma-Aldrich Chemicals Private Limited
  • Product Name:NF-κBActivationInhibitor-CAS545380-34-5-Calbiochem
  • Products Intro:Brand:sigma aldrich | Product Number:481406 | Purity:TheNF-κBActivationInhibitor,alsoreferencedunderCAS545380-34-5,controlsthebiologi
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:QNZ
  • Products Intro:Brand:ajchemicals | Product Number:JDH-35995 | Purity:98+%
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:QNZ
  • Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
  • Company Type: Reagent
  • Country/Region: CHINA
  • Product Name:QNZ
  • Products Intro:Purity: 99.17% | Package: 1mg;36USD|2mg;52USD|5mg;85USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE
  • Products Intro:Purity: 0.99summer | Package: 5KG;1KG | CustNote: Summer 618
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Methyl 3-amino-2-fluorobenzoate
  • Product Name:6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:QNZ EVP4593
  • Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: QNZ EVP4593
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: sarms
  • Product Name:QNZ
  • Products Intro:Purity: NLT 98% | CustNote: MC559672
  • Company Type: Manufacturer
  • Country/Region: CHINA
  • Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
  • Product Name:QNZ;CAY10470;EVP4593
  • Products Intro:Package: 1 mL * 10mM (in DMSO);10 mg;100 mg;2 mg;25 mg;5 mg;50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Reagent
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE
  • Products Intro:Package: 1kg, 5kg, 25kg, 50kg, 200kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Tris (hydroxymethyl) aminoethane,9-phenylcarbazole,2-Methylimidazole,Trifluoromethanesulfonic acid,1-Adamantanecarboxylic acid

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