BAY 11-7085
BAY 11-7085
- CAS:
- 196309-76-9
- MF:
- C13H15NO2S
- MW:
- 249.33
Suppliers by country/region
Company Type
Properties
- Melting point:
- 80-82℃
- Boiling point:
- 407.1±45.0 °C(Predicted)
- Density
- 1.144
- Flash point:
- 200℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: >25 mg/mL, soluble
- form
- solid
- color
- white
- Sensitive
- Light Sensitive
- InChIKey
- VHKZGNPOHPFPER-ONNFQVAWSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- WGK Germany
- 3
- RTECS
- UD1312500
- HS Code
- 29309090
Use
In the classical pathway of NF-κB activation, phosphorylation of the inhibitor of NF-κB (IκBα) releases the inhibitor from NF-κB, allowing IκBα degradation and NF-κB activation and nuclear import. BAY-11-7085 is an irreversible inhibitor of IκBα phosphorylation, preventing activation of NF-κB by cytokines and lipopolysaccharide (IC50 = 10 μM). It blocks gene expression that is regulated through the classical pathway of NF-κB activation and in this way blocks apoptosis, cell adhesion, and inflammation. BAY-11-7085 is also used to study IκBα actions that are independent of NF-κB signaling.
0 India supplier list of "BAY 11-7085"
- Product Name:Bay11-7085
- Products Intro:Brand:sigma aldrich | Product Number:B5681 | Purity:≥98%(HPLC),solid
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:BAY11-7085
- Products Intro:Brand:tcichemicals | Product Number:B4845
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:BAY11-7085
- Products Intro:Brand:ajchemicals | Product Number:JDH-26511 | Purity:98%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:BAY11-7085
- Products Intro:Brand:clearsynth | Product Number:CS-T-04779
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Bay 11-7085
- Products Intro:Purity: 98% HPLC | Package: 5MG;10MG;50MG;100MG,1G,5G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:BAY 11-7085
- Products Intro:Purity: 99% | Package: 1g;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1g
- Product Name:BAY 11-7085
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Bay 11-7085
- Products Intro:Purity: 98% (HPLC) | Package: $81.9/1g;$367.9/5g;Bulk package | CustNote: 98% (HPLC)
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:BAY 11-7085
- Products Intro:Purity: 98%
- Company Type: Reagent
- Country/Region: CHINA
-
10mg$127.00
- Product Name:Bay 11-7085
- Products Intro:Brand: Sigma-Aldrich | Product Number: B5681 | Purity: ≥98% (HPLC), solid
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof