Actinomycin D
Actinomycin D
- CAS:
- 50-76-0
- MF:
- C62H86N12O16
- MW:
- 1255.42
Suppliers by country/region
Company Type
Properties
- Melting point:
- 251-253 °C
- Boiling point:
- 848°C (rough estimate)
- Density
- 1.0757 (rough estimate)
- refractive index
- 1.5700 (estimate)
- Flash point:
- 87℃
- storage temp.
- 2-8°C
- solubility
- ethanol, DMSO: Stable in aqueous solutions at 2-8 °C.soluble
- form
- powder
- pka
- 8.94±0.70(Predicted)
- color
- red, powder
- optical activity
- [α]/D alpha: 28/D (Rotation: -315 degrees (c=0.25% in methanol))
- Water Solubility
- SOLUBLE
- Merck
- 13,2828
- BRN
- 605235
- Stability:
- Stable, but light sensitive, especially in dilute solution. Incompatible with strong acids, strong bases, strong oxidizing agents. Combustible.
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H300-H350-H360FD
- Precautionary statements
- P201-P202-P264-P270-P280-P301+P310
- Hazard Codes
- T+
- Risk Statements
- 28-61-40-45-26/27/28
- Safety Statements
- 53-36/37/39-45-1-36/37-28-22
- RIDADR
- UN 3462 6.1/PG 2
- WGK Germany
- 3
- RTECS
- AU1575000
- F
- 8-10-21
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 29419000
- Toxicity
- LD50 oral in rat: 7200ug/kg
Use
Actinomycin D is the most studied member of a family of unique bicyclic depsipeptides produced by several Streptomyces species. The depsipeptides are linked by a heterocyclic benzoxazone "anchor" that gives the metabolites a highly distinctive red/orange colour. Actinomycin D exhibits potent antibiotic and antitumor activity via DNA intercalation leading to the inhibition of nucleic acid synthesis. Tumor cell death has been demonstrated to occur by apoptosis.
6 India supplier list of "Actinomycin D"
- Product Name:Actinomycin D
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:ActinomycinD
- Products Intro:Brand:sigma aldrich | Product Number:A1410 | Purity:fromStreptomycessp.,~98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Actinomycin d 95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.108256
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Actinomycin D
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:ActinomycinD
- Products Intro:Brand:chemsworth | Product Number:185805869
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:ActinomycinD(AMD)extrapure,98%
- Products Intro:Brand:trivenichemical | Product Number:28269
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Dactinomycin
- Products Intro:Brand:clearsynth | Product Number:CS-T-14329
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Dactinomycin
- Company Type: Reagent
- Country/Region: Nagpur,INDIA
- Product Name:DACTINOMYCIN
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Actinomycin D
- Company Type: Reagent
- Country/Region: Gujarat,INDIA