Tazobactam acid
Tazobactam acid
- CAS:
- 89786-04-9
- MF:
- C10H12N4O5S
- MW:
- 300.29
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Properties
- Melting point:
- 115-145℃
- Boiling point:
- 77℃
- Density
- 1.92±0.1 g/cm3(Predicted)
- RTECS
- XI0191400
- Flash point:
- >110°(230°F)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated)
- pka
- 2.33±0.40(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- Soluble in water
- Stability:
- Light Sensitive
- InChI
- InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
- InChIKey
- LPQZKKCYTLCDGQ-WEDXCCLWSA-N
- SMILES
- N12[C@@]([H])(CC1=O)S(=O)(=O)[C@@](C)(CN1C=CN=N1)[C@@H]2C(O)=O
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Danger
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- HS Code
- 2941106000
Use
Tazobactam is a penicillanic acid sulfone that is similar instructure to sulbactam. It is a more potent β-lactamaseinhibitor than sulbactam and has a slightly broader spectrumof activity than clavulanic acid. It has very weak antibacterialactivity. Tazobactam is available in fixed-dose, injectablecombinations with piperacillin, a broad-spectrum penicillinconsisting of an 8:1 ratio of piperacillin sodium to tazobactamsodium by weight and marketed under the trade name Zosyn.The pharmacokinetics of the two drugs are very similar. Bothhave short half-lives (t1/2 ~1 hour), are minimally proteinbound, experience very little metabolism, and are excreted inactive forms in the urine in high concentrations.Approved indications for the piperacillin–tazobactamcombination include the treatment of appendicitis, postpartumendometritis, and pelvic inflammatory disease caused byβ-lactamase–producing E. coli and Bacteroides spp., skin andskin structure infections caused by β-lactamase–producingS. aureus, and pneumonia caused by β-lactamase–producingstrains of H. influenzae.
4 India supplier list of "Tazobactam acid"
- Product Name:Tazobactam
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Tazobactam
- Products Intro:Brand:sigma aldrich | Product Number:PHR1686 | Purity:PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Tazobactam
- Products Intro:Brand:synzeal | Product Number:821372279
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Tazobactam Acid
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Tazobactam
- Products Intro:Brand:pharmaffiliates | Product Number:PA2075000
- Company Type: Trader
- Country/Region: INDIA