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Abacavir

Abacavir

CAS:
136470-78-5
MF:
C14H18N6O
MW:
286.33

Properties

Melting point:
165°
alpha 
D20 -59.7°; 43620 -127.8°; 36520 -218.1° (c = 0.15 in methanol)
Boiling point:
636.0±65.0 °C(Predicted)
Density 
1.70±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
5.01(at 25℃)
color 
Off-White to Pale Beige
Merck 
14,1
BCS Class
3

Safety Information

Symbol(GHS) 

GHS08
Signal word 
Danger
Hazard statements 
H361-H317-H334-H341
Precautionary statements 
P501-P261-P272-P202-P201-P280-P284-P302+P352-P308+P313-P362+P364-P304+P340-P333+P313-P405
RTECS 
GY5979200
HS Code 
2933.99.7500

Use

Abacavir is a nucleoside reverse transcriptase inhibitorNRTI that has been approved for use in combination therapiesfor the treatment of HIV and AIDS. Once in the tissues,it is metabolized by stepwise phosphorylation to themonophosphate, diphosphate, and triphosphate. Abacavir ishighly bioavailable (>75%) and is effective by the oralroute. It penetrates the blood-brain barrier efficiently.Abacavir has been reported to produce life-threatening hypersensitivityreactions in some patients.

63 India supplier list of "Abacavir"

  • Product Name:Abacavir
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Abacavir
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Abacavir
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Abacavir
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Hyderabad,INDIA
  • Product Name:Abacavir
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Abacavir
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:N-Nitroso Abacavir
  • Products Intro:Purity: 98% | Package: 50 MG; 100 MG; 250 MG ; 1.5 GM
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Abacavir
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:Abacavir
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Tamil Nadu,INDIA
  • Product Name:Abacavir
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Tamil Nadu,INDIA

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