ABT-199
ABT-199
- CAS:
- 1257044-40-8
- MF:
- C45H50ClN7O7S
- MW:
- 868.44
Suppliers by country/region
Company Type
Properties
- Melting point:
- >150°C (dec.)
- Density
- 1.340±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly)
- form
- Yellow solid.
- pka
- 4.09±0.10(Predicted)
- color
- Light Yellow to Yellow
- InChIKey
- LQBVNQSMGBZMKD-UHFFFAOYSA-N
- SMILES
- C(NS(C1=CC=C(NCC2CCOCC2)C([N+]([O-])=O)=C1)(=O)=O)(=O)C1=CC=C(N2CCN(CC3CCC(C)(C)CC=3C3=CC=C(Cl)C=C3)CC2)C=C1OC1=CN=C2NC=CC2=C1
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H361-H372
- Precautionary statements
- P201-P202-P281-P308+P313-P405-P501-P260-P264-P270-P314-P501
Use
ABT-199, also known as venetoclax, is a small, oral chemical molecule used for the treatment of chronic lymphocytic leukemia (CLL) associated with a specific chromosomal abnormality. As a second line treatment drug of CLL, ABT-199 take effects through acting as a BH3-mimetic and inhibitor of Bcl-2 (the anti-apoptotic B-cell lymphoma-2protein), further inducing apoptosis of CLL cells but not platelets. It also has the potential for the treatment of ER-positive breast cancer.
11 India supplier list of "ABT-199"
- Product Name:Venetoclax
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Venetoclax
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Venetoclax
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Venetoclax
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:ABT-199
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Venclexta
- Company Type: Reagent
- Country/Region: Delhi,INDIA
- Product Name:Venetoclax
- Products Intro:Brand:pharmaffiliates | Product Number:PA2236000
- Company Type: Trader
- Country/Region: Haryana,INDIA