Auranofin
Auranofin
- CAS:
- 34031-32-8
- MF:
- C20H34AuO9PS
- MW:
- 678.48
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Properties
- Melting point:
- 112-115°
- storage temp.
- room temp
- solubility
- DMSO: ≥5mg/mL
- form
- solid
- color
- Crystals
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Signal word
- Danger
- Hazard statements
- H301-H361
- Hazard statements
- H301-H361
- Precautionary statements
- P201-P202-P264-P270-P280-P301+P310
- Precautionary statements
- P201-P202-P264-P270-P280-P301+P310
- Hazard Codes
- Xn
- Risk Statements
- 63-22
- Safety Statements
- 36/37
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
- RTECS
- MD6500000
- Toxicity
- LD50 in rats, mice (mg/kg): 265, 310 orally (Payne, Walz)
Use
Auranofin is a new oral gold-based antiarthritis drug. Auranofin inhibits various leukocyte activation pathways at multiple sites. Auranofin inhibits the release of inflammatory mediators from human m acrophages, basophils, and pulmonary mast cells. Auranofin is an efficient inducer of mitochondrial membrane permeability transition pore in the presence of calcium ions related to its inhibition of m itochondrial thioredoxin reductase.
1 India supplier list of "Auranofin"
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- Product Name:Auranofin
- Products Intro:Brand:sigma aldrich | Product Number:A6733 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA