Epothilone D
Epothilone D
- CAS:
- 189453-10-9
- MF:
- C27H41NO5S
- MW:
- 491.68
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Company Type
Properties
- Melting point:
- 63-66°C
- alpha
- D22 -61.3° (c = 2.5 in methanol)
- Boiling point:
- 663.7±55.0 °C(Predicted)
- Density
- 1.084±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Soluble in DMSO
- form
- solid
- pka
- 13.47±0.70(Predicted)
- color
- white to off-white
Safety Information
Use
Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.
2 India supplier list of "Epothilone D"
- Product Name:EpothiloneD
- Products Intro:Brand:clearsynth | Product Number:CS-T-54100
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Epothilone D
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Epothilone D
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:EpothiloneD(synthetic)
- Products Intro:Brand:pharmaffiliates | Product Number:PA050721000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-, (4S,7R,8S,9S,13Z,16S)-
- Products Intro:Purity: 99% | Package: 100g ;1KG ;5KG 25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: OLED/LCD chemicals,Reactive Mesogens,Silane,Silicon
- Product Name:Epothilone D
- Products Intro:Purity: as in COA | Package: as customers' requirements
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Epothilone D
- Products Intro:Purity: 98% | Package: 25G;50G;100G;500G;1KG;10KG;50KG
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:epothilone d
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Epothilone D
- Products Intro:Purity: Min98% HPLC | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1KG
- Product Name:Epothilone D
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
$1.10/ 1g