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Fumagillin

FUMAGILLIN

CAS:
23110-15-8
MF:
C26H34O7
MW:
458.54

Properties

Melting point:
194-195℃
alpha 
D25 -26.6° (c = 1 in 95% ethanol)
Boiling point:
484.03°C (rough estimate)
Density 
1.1368 (rough estimate)
refractive index 
1.5800 (estimate)
Flash point:
2℃
storage temp. 
2-8°C
solubility 
ethanol: 1 mg/mL
form 
powder
pka
4.27±0.10(Predicted)
color 
white
Sensitive 
Air Sensitive
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey
NGGMYCMLYOUNGM-ZILXAVPASA-N
LogP
3.260 (est)

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H302
Precautionary statements 
P264-P270-P301+P312-P501
Hazard Codes 
Xn,F
Risk Statements 
22-36-20/21/22-11
Safety Statements 
36-36/37-16-24/25
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
RTECS 
HE1750000
HS Code 
29419090
Toxicity
LD50 in mice (mg/kg): ~800 s.c. (DiPaolo)

Use

Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. It is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-inf ective and antiangiogenic agent. Fumagillin is a polyene mycotoxin isolated from Aspergillus fumigatus in 1951 as a potent antiprotozoan for the treatment of amoebiasis. More recently, fumagillin has been shown to inhibit endothelial cell proliferation and angiogenesis by inhibiting methionine aminopeptidase-2 (MetAP-2).

3 India supplier list of "FUMAGILLIN"

  • Product Name:Fumagillin,Aspergillusfumigatus-CAS23110-15-8-Calbiochem
  • Products Intro:Brand:sigma aldrich | Product Number:344845 | Purity:Antiprotozoalagentandangiogenesisinhibitor.
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Fumagillin 90% HPLC
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.090667
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Fumagillin
  • Products Intro:Brand:clearsynth | Product Number:CS-T-24929
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:FUMAGILLIN
  • Company Type: Reagent
  • Country/Region: Haryana,INDIA
  • Product Name:FUMAGILLIN
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Fumagillin
  • Products Intro:Brand:pharmaffiliates | Product Number:PA061630000
  • Company Type: Trader
  • Country/Region: Haryana,INDIA
  • Product Name:nicotinomycin
  • Products Intro:Purity: 98%+ | Package: G/bottle; Kg/bag; 25kg/barrel
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Ginsenoside,propoxate,Icaritin,Tadalafil,Argireline

    $0.00/ 25KG

  • Product Name:FUMAGILLIN
  • Products Intro:Purity: 99% | Package: 25KG
  • Company Type: Service provider
  • Country/Region: CHINA
  • Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
2Photos

    $20.70/ 1kg

  • Product Name:Fumagillin
  • Products Intro:Purity: 99%|Package: 1kg;20.70;USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: acetic acid,Ethyl oleate,Hypophosphorous acid,tetramisole,OPP

    $1.00/ 1g

  • Product Name:fumagillin
  • Products Intro:Purity: 99% | Package: 1g;1USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 1401708-83-5,307297-39-8,62304-98-7,170851-70-4,40077-57-4

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