MYRIOCIN
MYRIOCIN
- CAS:
- 35891-70-4
- MF:
- C21H39NO6
- MW:
- 401.54
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Properties
- Melting point:
- 170-172℃
- Boiling point:
- 636.7±55.0 °C(Predicted)
- Density
- 1.123±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- methanol: 2 mg/mL
- form
- powder
- pka
- 1.79±0.50(Predicted)
- color
- off-white
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months.
- InChIKey
- ZZIKIHCNFWXKDY-XFXZXTDPSA-N
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310-P405-P501
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22
- Safety Statements
- 24/25
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- JX3890000
- HS Code
- 29225090
Use
Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the first step of sphingolipid biosynthesis. It disrupts substratum adhesion of melanoma cells. It also suppresses cell proliferation in the murine cytotoxic T cell line CTLL-2 (IC50 = 15 nM) via apoptosis. Myriocin suppresses replication of the hepatitis C virus in a murine model.[Cayman Chemical]
0 India supplier list of "MYRIOCIN"
- Product Name:Myriocin,Myceliasterilia-CAS35891-70-4-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:476300 | Purity:Apotentimmunosuppressant.
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Myriocin
- Products Intro:Purity: 0.99 | Package: 100g;1kg;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA