Panitumumab
Panitumumab
- CAS:
- 339177-26-3
- MF:
- MW:
- 0
Suppliers by country/region
Company Type
Properties
- storage temp.
- Store at -20°C
- form
- Liquid
- color
- Colorless to light yellow
Safety Information
Use
Panitumumab is a recombinant, fully human IgG2 kappa monoclonal antibody that is highly selective for the epidermal growth factor receptor (EGFR), and it is indicated for the treatment of EGFR-expressing, metastatic colorectal carcinoma (mCRC) with disease progression on or following fluoropyrimidine-, oxaliplatin-, and irinotecan-containing chemotherapy regimens. Overexpression of EGFR is detected in many human cancers, including those of the colon and rectum. Panitumumab blocks the binding of ligands such as epidermal growth factor (EGF) and transforming growth factor (TGF-a) to various EGFR-expressing cell lines, which results in inhibition of EGF-dependent tumor cell activation, induction of apoptosis, and decreased pro-inflammatory cytokine and vascular growth factor production. In vitro, panitumumab binds EGFR with high affinity (KD ? 50pM; IC50 ? 3 nM) in human cervical epidermal cell line A-431. .
0 India supplier list of "Panitumumab"
- Product Name:Panitumumab
- Products Intro:Brand:clearsynth | Product Number:CS-O-35238
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Panitumumab
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
$1.10/ 1g
- Product Name:Panitumumab
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:Panitumumab (anti-EGFR)
- Products Intro:Purity: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human I | Package: $49.9/100μg;$207.9/1mg;$627.9/5mg;$897.9/10mg;Bulk package | CustNote: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:Research Grade Pintumomab (DHJ57401)
- Products Intro:Purity: PAGE:>95% | Package: 100ug;1mg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Panitumumab
- Products Intro:Purity: 98% | Package: 10MG/RMB 788
- Company Type: Trader
- Country/Region: CHINA
-
001$700.00003$1900.00
- Product Name:Panitumumab
- Products Intro:Brand：dcchemicals | Product Number：013330
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Panitumumab
- Products Intro:Brand：a2bchem | Product Number：AF69816
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Panitumumab
- Products Intro:Brand：medicalisotopes | Product Number：17622
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:Panitumumab
- Products Intro:Purity: 97% (API) | Package: 2mg/vial ， for other packages pls just contact for details
- Company Type: Service provider
- Country/Region: CHINA