Pepstatin
Pepstatin
- CAS:
- 26305-03-3
- MF:
- C34H63N5O9
- MW:
- 685.89
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Company Type
Properties
- Melting point:
- 233 °C (dec.)(lit.)
- alpha
- D27 -90.3° (c = 0.288 in methanol)
- Boiling point:
- 695.91°C (rough estimate)
- Density
- 1.1340 (rough estimate)
- refractive index
- 1.7500 (estimate)
- storage temp.
- 2-8°C
- solubility
- 10% acetic acid in methanol: 1 mg/mL
- pka
- 4.17±0.10(Predicted)
- form
- White solid
- color
- Colorless needles
- optical activity
- Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C).
- Water Solubility
- It is soluble in 10% (v/v) acetic acid in methanol (9:1 methanol:acetic acid) (1 mg/ml), ethanol (1-2 mg/ml with heat up to 60°C), DMSO (5 mg/ml), methanol (1 mg/ml), and acetic acid. Insoluble in benzene, chloroform, water, 1 M NaOH, and ether.
- BRN
- 2201362
- Stability:
- Stable. Incompatible with strong bases, strong acids.
- InChIKey
- JKGWASGTXVCDML-LXTPJMTPSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- Safety Statements
- 22-24/25
- WGK Germany
- 2
- RTECS
- SC6155000
- F
- 10
- HS Code
- 29241990
- Toxicity
- LD50 in mice, rats, rabbits, dogs (mg/kg): 1090, 875, 820, 450 i.p.; all >2000 orally (Umezawa, 1970)
Use
As an aspartic proteases irreversible inhibitor, Pepstain A can be used in conjunction with E64-d and Leupeptin A to inhibit the degradation of autophagic cargo inside autophagosomes.
1 India supplier list of "Pepstatin"
- Product Name:Anti-CATD(lightchain,Cleaved-Gly65)antibodyproducedinrabbit
- Products Intro:Brand:sigma aldrich | Product Number:SAB4500553 | Purity:affinityisolatedantibody
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Pepstatin a 95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.168499
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:PepstatinA
- Products Intro:Brand:chemsworth | Product Number:741098477 | Purity:~95%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:PepstatinA
- Products Intro:Brand:ajchemicals | Product Number:JDH-35429 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:PepstatinA
- Products Intro:Brand:ottokemi | Product Number:P2999 | Purity:90%
- Company Type: Trader
- Country/Region: Mumbai,INDIA
- Product Name:Pepstain A
- Products Intro:Purity: 98% HPLC | Package: 5mg; 25mg; 100mg; 1g; 5g; 25g;100g | CustNote: B0230
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Pepstatin
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:Pepstatin A
- Products Intro:Purity: 98% | Package: 1KG;10KG;50KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Pepstatin A
- Products Intro:Purity: >98% | Package: 500mg | CustNote: BOC Sciences also provides custom synthesis services for Pepstatin A.
- Company Type: Trader
- Country/Region: UNITED STATES