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Roscovitine

ROSCOVITINE

CAS:
186692-46-6
MF:
C19H26N6O
MW:
354.45

Properties

Melting point:
106~107℃
Boiling point:
577.5±60.0 °C(Predicted)
Density 
1.3
storage temp. 
-20°C
solubility 
Soluble in DMSO (up to 10 mg/ml, with warming) or in Ethanol (up to 10 mg/ml).
pka
14.56±0.10(Predicted)
form 
White to off-white solid
color 
White
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey
BTIHMVBBUGXLCJ-OAHLLOKOSA-N

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H302+H312+H332-H315-H319
Precautionary statements 
P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29335990

Use

Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung c ancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.

0 India supplier list of "ROSCOVITINE"

  • Product Name:Roscovitine-CAS186692-46-6-Calbiochem
  • Products Intro:Brand:sigma aldrich | Product Number:557360 | Purity:Apotent,reversible,andselectiveinhibitorofCdksthatexhibitsabout10-foldgreatereff
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Roscovitine
  • Products Intro:Brand:ajchemicals | Product Number:JDH-36177 | Purity:98+%
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Seliciclib-D7
  • Products Intro:Brand:clearsynth | Product Number:CS-B-00209
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:Roscovitine
  • Products Intro:Package: as customers' requirement
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Roscovitine
  • Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
  • Company Type: Reagent
  • Country/Region: CHINA

    $1.00/ 1KG

  • Product Name:ROSCOVITINE
  • Products Intro:Purity: 98% | Package: 1KG;1USD
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:roscovitine
  • Products Intro:Purity: 0.99 | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Seliciclib;Roscovitine;R-roscovitine;CYC202
  • Products Intro:Purity: 98.00% | Package: 1 mL * 10mM (in DMSO);10 mg;100 mg;200 mg;25 mg;5 mg;50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:ROSCOVITINE
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Roscovitine
  • Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot sales
  • Company Type: Trader
  • Country/Region: CHINA

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