Roscovitine
ROSCOVITINE
- CAS:
- 186692-46-6
- MF:
- C19H26N6O
- MW:
- 354.45
Suppliers by country/region
Company Type
Properties
- Melting point:
- 106~107℃
- Boiling point:
- 577.5±60.0 °C(Predicted)
- Density
- 1.3
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to 10 mg/ml, with warming) or in Ethanol (up to 10 mg/ml).
- pka
- 14.56±0.10(Predicted)
- form
- White to off-white solid
- color
- White
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
- InChIKey
- BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302+H312+H332-H315-H319
- Precautionary statements
- P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29335990
Use
Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung c ancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.
0 India supplier list of "ROSCOVITINE"
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- Product Name:Roscovitine-CAS186692-46-6-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:557360 | Purity:Apotent,reversible,andselectiveinhibitorofCdksthatexhibitsabout10-foldgreatereff
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:ROSCOVITINE
- Products Intro:Purity: 98% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$1.00/ 1KG
- Product Name:Seliciclib;Roscovitine;R-roscovitine;CYC202
- Products Intro:Purity: 98.00% | Package: 1 mL * 10mM (in DMSO);10 mg;100 mg;200 mg;25 mg;5 mg;50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits