Rubitecan
Rubitecan
- CAS:
- 91421-42-0
- MF:
- C20H15N3O6
- MW:
- 393.35
Suppliers by country/region
Company Type
Properties
- Melting point:
- 182-186°C
- alpha
- D23 +27° (c = 0.2 in CH3OH-CHCl3, 1:4)
- Boiling point:
- 816.3±65.0 °C(Predicted)
- Density
- 1.63
- Flash point:
- 106℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Chloroform, Methanol
- form
- Solid
- pka
- 11.16±0.20(Predicted)
- color
- Yellow
- Merck
- 14,8288
Safety Information
Use
Rubitecan, marketed by Supergen as Orathecin, is a promising oral treatment for solid melanoma, prostate, breast, ovarian, and other cancers, as well as leukemia. It is a derivative of camptothecin, a topoisomerase inhibitor known from Chinese Traditional Medicine. It selectively targets the critical S-stage of cellular reproduction particularly in acidic environments, as in many cancer cells relaxing DNA supercoiling and generating lethal breaks in the DNA. Due to insolubility, its biological delivery mechanism is not yet effective, and it has not been approved for clinical use.
1 India supplier list of "Rubitecan"
- Product Name:Rubitecan
- Products Intro:Brand:sigma aldrich | Product Number:R3655
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Rubitecan 99% (HPLC), powder
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.085870
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Rubitecan
- Products Intro:Brand:clearsynth | Product Number:CS-T-61205
- Company Type: Trader
- Country/Region: INDIA
- Product Name:9-Nitrocamptothecin
- Products Intro:Brand:tcichemicals | Product Number:N0822
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:9-Nitrocamptothecin
- Products Intro:Purity: 0.98 | Package: 1KG;10KG;50KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Rubitecan
- Products Intro:Purity: >95%,98%,99% | Package: From mgs to grams,up to Kgs | CustNote: Can be customized in bulk scale
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:Rubitecan
- Products Intro:Purity: >=98% | Package: 100mg | CustNote: BOC Sciences also provides custom synthesis services for Rubitecan.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:rubitecan
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Rubitecan
- Products Intro:Purity: 0.99 | Package: 1kg,5kg,25kgs,200kgs;bulk
- Company Type: Trader
- Country/Region: CHINA