Tetracycline
Tetracycline
- CAS:
- 60-54-8
- MF:
- C22H24N2O8
- MW:
- 444.43
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Company Type
Properties
- Melting point:
- 175-177 °C(lit.)
- alpha
- D25 -257.9° (0.1N HCl); D25 -239° (methanol)
- Boiling point:
- 554.44°C (rough estimate)
- Density
- 1.3809 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- 2-8°C
- solubility
- 95% ethanol: soluble12.5mg/mL
- form
- powder
- pka
- pKa (50% aq DMF): 8.3, 10.2(at 25℃)
- color
- yellow to yellow orange
- optical activity
- [α]25/D -239° in methanol (Specific rotation ) &_& [α]25/D -257.9°, c = 0.1 M HCl mol (Specific rotation )
- Water Solubility
- Limited solubility in water. Soluble in 1M HCl with heating.
- Merck
- 13,9271
- BRN
- 2230417
- BCS Class
- 3
- Stability:
- Hygroscopic
- InChIKey
- OFVLGDICTFRJMM-WESIUVDSSA-N
Safety Information
- Symbol(GHS)
GHS07,GHS08,GHS09
- Signal word
- Warning
- Hazard statements
- H302-H361fd-H411
- Precautionary statements
- P202-P264-P270-P273-P301+P312-P308+P313
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 22-36-26
- WGK Germany
- 3
- RTECS
- QI8750000
- F
- 3-8-10
- HS Code
- 29413000
- Toxicity
- LD50 in rats, mice (mg/kg): 807, 808 orally (Goldenthal)
Use
Tetracycline is a linear, tetracyclic, broad spectrum antibiotic first prepared chemically by dechlorination of chlortetracycline and subsequently isolated from several Streptomyces species. Tetracycline has broad spectrum antibacterial and antiprotozoan activity, and acts by binding to the 30S and 50S ribosomal subunits blocking protein synthesis. Tetracycline is a pigment and, like many pigments, is degraded by light, oxygen, trace metal ions and pH variations. The purity of tetracycline is often variable, with significant levels of degradation products.
2 India supplier list of "Tetracycline"
- Product Name:(4S,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro- 3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene- 2-carboxamide
- Products Intro:Purity: 96% | Package: 25 mg, 50 mg , 100mg or 500 mg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Tetracycline
- Products Intro:Brand:sigma aldrich | Product Number:87128 | Purity:98.0-102.0%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Tetracycline 90.00%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.073148
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:OxytetracyclineEPImpurityB
- Products Intro:Brand:synzeal | Product Number:770887389
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Tetracycline
- Products Intro:Brand:trivenichemical | Product Number:101349199
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:TetracyclineD6
- Products Intro:Brand:clearsynth | Product Number:CS-O-15812
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Tetracycline
- Products Intro:Brand:pharmaffiliates | Product Number:PA1286080
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Tetracycline
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
$0.00/ 25KG
- Product Name:Tetracycline
- Products Intro:Purity: 99.0%min | Package: 1kg;|5kg;|10kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2-Chloromalonaldehyde,(R)-5,7-difluorochroman-4-ol,Cyclobutanecarboxylic acid,(Bromomethyl)cyclobutane,5-Amino-4-imidazolecarboxamide
$0.00-0.00 / 1kg
- Product Name:Tetracycline HCL
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA