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Zopiclone
Zopiclone
- CAS:
- 43200-80-2
- MF:
- C17H17ClN6O3
- MW:
- 388.81
Properties
- Melting point:
- 1780C
- Boiling point:
- 580.7±50.0 °C(Predicted)
- Density
- 1.1105 (estimate)
- Flash point:
- 2℃
- storage temp.
- Store at RT
- solubility
- DMSO: 2 mg/mL
- form
- Solid
- pka
- pKa ﹣1.5±0.1(10% ACN in aq. H2SO4 t = 25.0) (Uncertain)
- color
- White to Off-White
- Stability:
- Hygroscopic
- InChIKey
- GBBSUAFBMRNDJC-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H336
- Precautionary statements
- P261-P264-P270-P271-P301+P312-P304+P340+P312
- Hazard Codes
- Xn,Xi,F
- Risk Statements
- 20/21/22-36/37/38-62-36-11
- Safety Statements
- 26-36-36/37-16
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 3
- RTECS
- TL1425000
- HS Code
- 29339900
- Toxicity
- mouse,LD50,intramuscular,541mg/kg (541mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSIONBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY),Oyo Yakuri. Pharmacometrics. Vol. 26, Pg. 935, 1983.
Use
Zopiclone is an agonist at the type A -aminobutyric acid (GABA) receptor. It is a non-benzodiazepine hypnotic which was first reviewed in Drugs in 1986 and it is indicated for short-term treatment of insomnia. Zopiclone has a relatively low propensity to cause residual clinical effects (such as difficulty in waking or reduced morning concentration).
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