Zopiclone
- CAS No.
- 43200-80-2
- Chemical Name:
- Zopiclone
- Synonyms
- imovane;Zopiclone R-IsoMer CIV;6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate;Imobam;Amoban;Amovane;Sopivan;Limovan;Ximovan;CS-1331
- CBNumber:
- CB1401303
- Molecular Formula:
- C17H17ClN6O3
- Molecular Weight:
- 388.81
- MOL File:
- 43200-80-2.mol
- Modify Date:
- 2023/6/8 9:02:47
| Melting point | 1780C |
|---|---|
| Boiling point | 580.7±50.0 °C(Predicted) |
| Density | 1.1105 (estimate) |
| Flash point | 2℃ |
| storage temp. | Store at RT |
| solubility | DMSO: 2 mg/mL |
| form | Solid |
| pka | pKa ﹣1.5±0.1(10% ACN in aq. H2SO4 t = 25.0) (Uncertain) |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChIKey | GBBSUAFBMRNDJC-UHFFFAOYSA-N |
| CAS DataBase Reference | 43200-80-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Zopiclone(43200-80-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H336 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P301+P312-P304+P340+P312 | |||||||||
| Hazard Codes | Xn,Xi,F | |||||||||
| Risk Statements | 20/21/22-36/37/38-62-36-11 | |||||||||
| Safety Statements | 26-36-36/37-16 | |||||||||
| RIDADR | UN 1648 3 / PGII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TL1425000 | |||||||||
| HS Code | 29339900 | |||||||||
| Toxicity | mouse,LD50,intramuscular,541mg/kg (541mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSIONBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY),Oyo Yakuri. Pharmacometrics. Vol. 26, Pg. 935, 1983. | |||||||||
| NFPA 704 |
|
Zopiclone price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | Z-003 | Zopiclone solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? | 43200-80-2 | 1ML | ₹10041.5 | 2022-06-14 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| Z-003 | 1ML | ₹10041.5 | Buy |
Zopiclone Chemical Properties,Uses,Production
Description
Zopiclone is an effective hypnotic agent with a short duration of action. Although it interacts with the benzodiazepine receptor complex, it is reported to have minimal effects on memory, little synergy with alcohol, and low abuse potential.
Chemical Properties
Crystalline Solid
Uses
Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic
Definition
ChEBI: A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
World Health Organization (WHO)
Zopiclone was introduced as a sedative in 1985. It remains registered in several countries and the World Health Organization is not aware of any other country that has refused registration.
Zopiclone Preparation Products And Raw materials
Raw materials
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43200-80-2(Zopiclone)Related Search:
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Imovane, 4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
Zopiclone-d4
6-(5-Chloropyrid-2-y1)-5-(4-methylpiperazin-1-y1)car-bonyloxy-7-oxo-6，7-dihydro-5H-pyrrolo[3，4-b] pyrazine
Zopiclone solution
hrrtovane
Imobam
Zinovane
4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
Amobantes
Acetonitrile(Test Zopiclone, 1.0 mg/mL)
6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-Methyl-1-piperazinecarboxylate
6-(5-chloropyrid-2-yl)-5-(4-Methylpiperazin-1-yl)carbonyloxy-7-oxo-6,7-dihydro- 5H-pyrrolo[3,4-b]pyrazine
Zopiclone(IMovane)
4-METHYL-1-PIPERAZINECARBOXYLIC ACID 6-(5-CHLORO-2-PYRIDINYL)-6,7-DIHYDRO-7-OXO-5H-PYRROLO[3,4-B] PYRAZIN-5-YL ESTER
1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
27267 R.P.
27267r.p.
4-methyl-,6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-1-piperazinecarboxylicaci
ZOPICLONE
4-methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5h-pyrrolo[3,4-b]pyrazin-5-yl ester
4-METHYLPIPERAZINE-1-CARBOXYLIC ACID 6-(5-CHLORO-PYRIDIN-2-YL)-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PY
4-Methyl-1-piperazinecarboxylic acid ester with 6-(5-chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one
Amoban
Amovane
Imovance
oxo-5h-pyrrolo(3,4-b)pyrazin-5-ylester
RP-27267
Sopivan
Zimovane
Zopicclone
Limovan
Ximovan
4-Methyl-1-piperazine-d8-carboxylic Acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl Ester
Amoban-d8
Imovane-d8
Limovan-d8
RP-27267-d8
Sopivan-d8
Ximovan-d8
1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo3,4-bpyrazin-5-yl ester
1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester (9CI)
CS-1331
[6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate
Zopiclone, 1000ppm
Zopiclone (CRM)
ZOPICLONE +98%
Zopiclone (controlled)
Zopiclone USP/EP/BP
ZopicloneQ: What is
Zopiclone Q: What is the CAS Number of
Zopiclone Q: What is the storage condition of
Zopiclone
Zopiclone R-Isomer CIV ((-)-(5R)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazi (1729118)
Zopiclone R-IsoMer CIV
imovane
6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate
43200-80-2
C17H17ClN6O3
C17H13D4ClN6O3
Isotopically Labeled Pharmaceutical Reference Standard
BUPHENYL