ZOTAROLIMUS
ZOTAROLIMUS
- CAS:
- 221877-54-9
- MF:
- C52H79N5O12
- MW:
- 966.21
Suppliers by country/region
Company Type
Properties
- Melting point:
- 100-105°C
- Boiling point:
- 1016.2±75.0 °C(Predicted)
- Density
- 1.25
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO, Methanol (Slightly)
- form
- Solid
- pka
- 10.40±0.70(Predicted)
- color
- White to Pale Yellow
Safety Information
- HS Code
- 29349990
Use
Zotarolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by preparation of the 42-triflate ester, followed by displacement with tetrazole and purification of the two isomeric products. This structural change affords a less bioavailable product, a preferred profile for some applications. Like all tacrolimus analogues, zotarolimus binds to a receptor protein (FKBP12). The complex then binds to mTOR preventing it from interacting with target proteins. Zotarolimus is extensively cited in the literature with over 200 citations.
0 India supplier list of "ZOTAROLIMUS"
- Product Name:Zotarolimus
- Products Intro:Brand:clearsynth | Product Number:CS-T-62856
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Zotarolimus
- Products Intro:Brand:pharmaffiliates | Product Number:PA2610000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Zotarolimus
- Products Intro:Purity: As coa | Package: As request | CustNote: 221877-54-9
- Company Type: Trader
- Country/Region: CHINA
- Product Name:ZOTAROLIMUS
- Products Intro:Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name: ZOTAROLIMUS
- Products Intro:Purity: 85.0-99.8% | Package: 1g;1USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Methyl 3-amino-2-fluorobenzoate
- Product Name:ZOTAROLIMUS
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Zotarolimus
- Products Intro:Purity: >98% | CustNote: BOC Sciences also provides custom synthesis services for Zotarolimus.
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:ZOTAROLIMUS
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceuticals,intermediates,fine chemicals,screening compounds,building blocks
- Product Name:Zotarolimus；ABT-578;A 179578
- Products Intro:Package: 1 mg；1 mL * 10mM (in DMSO)；10 mg；2 mg；25 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:ZOTAROLIMUS
- Products Intro:Purity: 99 | Package: 5KG;1KG,25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Palmitoylethanolamide,GHK-Cu,Copper tripeptide-1,Nicotinamide Riboside Chloride,NMN,Ergothioneine