Orantinib (SU6668)
Orantinib (SU6668)
- CAS:
- 252916-29-3
- MF:
- C18H18N2O3
- MW:
- 310.35
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Company Type
Properties
- Melting point:
- 252-254 °C
- Boiling point:
- 590.5±50.0 °C(Predicted)
- Density
- 1.328±0.06 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4?+-.0.10(Predicted)
- color
- Orange to Brown
Safety Information
- Symbol(GHS)
GHS05,GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H301-H318-H361-H372
- Precautionary statements
- P201-P202-P260-P264-P270-P280-P301+P310-P321-P330-P305+P351+P338-P308+P313-P314-P405-P501
Use
3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid is a potent inhibitor of Flk-1/KDR, FGFR1 and PDGFRβ with Ki of 2.1 μM, 1.2 μM, and 8 nM, respectively. 3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid is a potent inhibitor of Flk-1/KDR, FGFR1 and PDGFRβ with Ki of 2.1 μM, 1.2 μM, and 8 nM, respectively. 3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid is an oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is substituted by a 2-(2-carboxyethyl)-3,5-dimethylpyrrol-3-yl group. It is an ATP-competitive inhibitor of the tyrosine kinase activity of fibroblast growth facto receptor 1.
1 India supplier list of "Orantinib (SU6668)"
- Product Name:SU-6668 >95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.089129
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:TSU-68
- Products Intro:Brand:clearsynth | Product Number:CS-T-45753
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:TSU-68
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
$1.00/ 1KG
- Product Name:3-[2,4-dimethyl-5-[(E)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
- Products Intro:Purity: 99% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Orantinib
- Products Intro:Purity: >=98% | Package: 100mg | CustNote: BOC Sciences also provides custom synthesis services for Orantinib.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:tsu-68
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Orantinib
- Products Intro:Purity: 98.01% | Package: 5mg;47USD|10mg;72USD|25mg;153USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Orantinib (SU6668)
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Orantinib SU6668 PDGFR inhibitor ab142156 SU-6668 tsu68 tsu-68
- Products Intro:Purity: 99% | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:TSU-68
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: pharmaceuticals,intermediates,fine chemicals,screening compounds,building blocks