ABT-199
ABT-199
- CAS:
- 1257044-40-8
- MF:
- C45H50ClN7O7S
- MW:
- 868.44
Suppliers by country/region
Company Type
Properties
- Melting point:
- >150°C (dec.)
- Density
- 1.340±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly)
- form
- Yellow solid.
- pka
- 4.09±0.10(Predicted)
- color
- Light Yellow to Yellow
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H361-H372
- Precautionary statements
- P201-P202-P281-P308+P313-P405-P501-P260-P264-P270-P314-P501
Use
ABT-199, also known as venetoclax, is a small, oral chemical molecule used for the treatment of chronic lymphocytic leukemia (CLL) associated with a specific chromosomal abnormality. As a second line treatment drug of CLL, ABT-199 take effects through acting as a BH3-mimetic and inhibitor of Bcl-2 (the anti-apoptotic B-cell lymphoma-2protein), further inducing apoptosis of CLL cells but not platelets. It also has the potential for the treatment of ER-positive breast cancer.
11 India supplier list of "ABT-199"
- Product Name:Venetoclax
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Venetoclax
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Venetoclax
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Venetoclax
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:ABT-199 >95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.089698
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Venetoclax
- Products Intro:Brand:synzeal | Product Number:173628377
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:VENETOCLAX
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:ABT-199
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:VENETOCLAX
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Venetoclax
- Products Intro:Brand:pharmaffiliates | Product Number:PA2236000
- Company Type: Trader
- Country/Region: Haryana,INDIA