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Adefovir

Adefovir

CAS:
106941-25-7
MF:
C8H12N5O4P
MW:
273.19

Properties

Melting point:
>260°C
Boiling point:
632.5±65.0 °C(Predicted)
Density 
1.88
storage temp. 
-20°C
solubility 
0.1 M NaOH: ≥5mg/mL
pka
pKa1 2.0, pKa2 6.8(at 25℃)
form 
powder
color 
white to beige
InChIKey
SUPKOOSCJHTBAH-UHFFFAOYSA-N

Safety Information

Symbol(GHS) 

GHS06
Signal word 
Danger
Hazard statements 
H301
Precautionary statements 
P301+P310
Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
2811
WGK Germany 
3
RTECS 
SZ6563500
HazardClass 
6.1
PackingGroup 
HS Code 
29339900

Use

Adefovir (Trade name: Preveon, Hepsera) is a prescription drug used for the treatment of chronic infections of hepatitis B virus. It can be formulated as the pivoxil prodrug adefovir dipivoxil. However, it shows no effect against HIV-1. As a orally administrated acyclic nucleotide analog reverse transcriptase inhibitor, it blocking the reproduction of HBV through inhibiting the reverse transcriptase in the body. One of its advantages over another anti-HBV drug, lamivudine is that it is much harder for the virus to develop resistance to it.

6 India supplier list of "Adefovir"

  • Product Name:Adefovir
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Adefovir
  • Products Intro:Brand:sigma aldrich | Product Number:SML0240 | Purity:≥98%(HPLC)
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:Adefovir 98% (HPLC)
  • Products Intro:Brand:Glrinnovations | OriginalID:GLR19.040801
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Adefovir
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:Adefovir
  • Products Intro:Brand:clearsynth | Product Number:CS-O-11586
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:TenofovirDesmethylImpurity
  • Products Intro:Brand:synzeal | Product Number:128552157
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:9-2-(phosphonomethoxy) Ethyl Adenine
  • Company Type: Reagent
  • Country/Region: Mumbai,INDIA
  • Product Name:Adefovir
  • Company Type: Reagent
  • Country/Region: Haryana,INDIA
  • Product Name:9-2-(phosphonomethoxy) Ethyl Adenine
  • Company Type: Reagent
  • Country/Region: Vadodara,INDIA
  • Product Name:Adefovir
  • Products Intro:Brand:ajchemicals | Product Number:JDH-26135 | Purity:99+%
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA

Adefovir Related Search:

Gemcitabine hydrochloride6-Aminocaproic acidp-AnisidineTris(hydroxymethyl)aminomethaneMethoxyacetic acid(Trifluoromethoxy)benzeneALTRENOGESTAdenineAnisoleMethoxydiethylboranem-Anisyl alcoholGlycine[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl esterAdefovir dipivoxil2,2-Dimethylpropanoic acid 1,1'-[[[[2-[6-[(2,2-dimethyl-1-oxopropyl)amino]-9H-purin-9-yl]ethoxy]methyl]phosphinylidene]bis(oxymethylene)] esterPropanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl esterPropanoic acid, 2,2-dimethyl-, [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]hydroxyphosphinyl]oxy]methyl esterTenofovir
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