Amphotericin B
Amphotericin B
- CAS:
- 1397-89-3
- MF:
- C47H73NO17
- MW:
- 924.08
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Company Type
Properties
- Melting point:
- >170°C
- alpha
- D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)
- Boiling point:
- 804.34°C (rough estimate)
- Density
- 1.34
- refractive index
- 1.5280 (estimate)
- storage temp.
- 2-8°C
- solubility
- sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20°C. Stable at 37°C for 3 days.
- form
- powder
- pka
- pKa ～5.7(DMF/H2O) (Uncertain)
- color
- yellow
- Water Solubility
- <0.1 g/100 mL at 21 ºC
- Sensitive
- Moisture & Light Sensitive
- Merck
- 13,590
- BRN
- 78342
- Stability:
- Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
- InChIKey
- APKFDSVGJQXUKY-INPOYWNPSA-N
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H372
- Precautionary statements
- P260-P264-P270-P314-P501
- Hazard Codes
- C,Xi,Xn,T
- Risk Statements
- 36/37/38-22-40-23/24/25
- Safety Statements
- 26-36/37/39-45-36-60-37
- RIDADR
- UN 1759 8/PG 3
- WGK Germany
- 3
- RTECS
- BU2625000
- F
- 8-10-21
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29419090
- Toxicity
- LD50 in mice (mg/kg): 88 i.p., 4 i.v. (Keim)
Use
Amphotericin B (Funizone) is an antifungal macrolide antibiotic produced by Streptomyces nodosus that has been used as an alternative, albeit more toxic, drug to the antimonials. See also Amebiasis (Amebic Dysentery) . It acts as a leishmanicide against the visceral and mucocutaneous forms of the disease. To overcome its potentially severe nephrotoxicity, the drug must be administered over an extended period of time.
35 India supplier list of "Amphotericin B"
- Product Name:Amphotericin B
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Amphotericin B
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Amphotericin B
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Amphotericin B
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Amphotericin B
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Amphotericin B
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:amphotericin b
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:Amphotericin B
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Himachal Pradesh,INDIA
- Product Name:Amphotericin
- Products Intro:Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Kerela,INDIA
- Product Name:Amphotericin B
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Gujarat,INDIA