BAY 11-7085
BAY 11-7085
- CAS:
- 196309-76-9
- MF:
- C13H15NO2S
- MW:
- 249.33
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Company Type
Properties
- Melting point:
- 80-82℃
- Boiling point:
- 407.1±45.0 °C(Predicted)
- Density
- 1.144
- Flash point:
- 200℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: >25 mg/mL, soluble
- form
- solid
- color
- white
- Sensitive
- Light Sensitive
- InChIKey
- VHKZGNPOHPFPER-ONNFQVAWSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- WGK Germany
- 3
- RTECS
- UD1312500
- HS Code
- 29309090
Use
In the classical pathway of NF-κB activation, phosphorylation of the inhibitor of NF-κB (IκBα) releases the inhibitor from NF-κB, allowing IκBα degradation and NF-κB activation and nuclear import. BAY-11-7085 is an irreversible inhibitor of IκBα phosphorylation, preventing activation of NF-κB by cytokines and lipopolysaccharide (IC50 = 10 μM). It blocks gene expression that is regulated through the classical pathway of NF-κB activation and in this way blocks apoptosis, cell adhesion, and inflammation. BAY-11-7085 is also used to study IκBα actions that are independent of NF-κB signaling.
0 India supplier list of "BAY 11-7085"
- Product Name:Bay11-7085
- Products Intro:Brand:sigma aldrich | Product Number:B5681 | Purity:≥98%(HPLC),solid
- Company Type: Trader
- Country/Region: INDIA
$1.00/ 1g
- Product Name:BAY 11-7085
- Products Intro:Purity: 99% | Package: 1g;1USD
- Company Type: Trader
- Country/Region: CHINA