Everolimus
Everolimus
- CAS:
- 159351-69-6
- MF:
- C53H83NO14
- MW:
- 958.22
Suppliers by country/region
Company Type
Properties
- Melting point:
- NA
- Boiling point:
- 998.7±75.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- Flash point:
- 2℃
- storage temp.
- -20°C
- solubility
- Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 100 mg/ml).
- form
- solid
- pka
- 10.40±0.70(Predicted)
- color
- White
- Water Solubility
- Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.
- Stability:
- Hygroscopic
- InChIKey
- HKVAMNSJSFKALM-GKUWKFKPSA-N
Safety Information
- Symbol(GHS)
GHS08,GHS09
- Signal word
- Warning
- Hazard statements
- H351-H361fd-H373-H410
- Precautionary statements
- P202-P260-P273-P280-P308+P313-P391
- Hazard Codes
- T,Xn,F
- Risk Statements
- 48/25-36-20/21/22-11
- Safety Statements
- 45-36/37-26-16
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 2
- F
- 10
- HS Code
- 29349990
Use
Everolimus is a derivative of Rapamycin(sirolimus), and works similarly to Rapamycin as an mTOR(mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors, Everolimus takes effect solely on the mTORC1 protein and not on the mTORC2 protein[1]. In transplantation medicine, it is marketed under the trade names Zortress(USA) and Certican(Europe). It has been also used for the treatment of tumors, being marketed as Afinitor(general tumours) and Votubia(tumours as a result of TSC) in oncology.
33 India supplier list of "Everolimus"
- Product Name:Everolimus
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Uttar Pradesh,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Everolimus
- Products Intro:Purity: 99% | Package: 1kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Kerela,INDIA