OSI-420
OSI-420
- CAS:
- 183321-86-0
- MF:
- C21H21N3O4
- MW:
- 379.41
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Company Type
Properties
- Melting point:
- 140-142°C
- Density
- 1.30
- storage temp.
- -20°C Freezer
- solubility
- insoluble in H2O; insoluble in EtOH; ≥51 mg/mL in DMSO
- form
- A crystalline solid
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Use
OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
1 India supplier list of "OSI-420"
- Product Name:Erlotinib6-O-DesmethylMetabolite
- Products Intro:Brand:synzeal | Product Number:183311109
- Company Type: Trader
- Country/Region: INDIA
- Product Name:OSI-420
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Erlotinib6-O-DesmethylMetabolite
- Products Intro:Brand:pharmaffiliates | Product Number:PA050141022
- Company Type: Trader
- Country/Region: INDIA