TOLBUTAMIDE
TOLBUTAMIDE
- CAS:
- 64-77-7
- MF:
- C12H18N2O3S
- MW:
- 270.35
Suppliers by country/region
Company Type
Properties
- Melting point:
- 128-130°C
- Density
- 1.2450
- refractive index
- 1.6360 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in chloroform.
- pka
- pKa 5.32(H2O t = 37) (Uncertain)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 0.14g/L(25 ºC)
- Merck
- 14,9507
- BRN
- 1984428
- Specific Activity
- 50-60 mCi/mmol
- Concentration
- 0.1 mCi/ml
- Solvent
- Ethanol
- Stability:
- Stable. Combustible.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H317
- Precautionary statements
- P261-P280g-P301+P312a-P321-P333+P313-P501a
- Hazard Codes
- F,Xn
- Risk Statements
- 20/21/22-40-43-36-11
- Safety Statements
- 26-36/37/39-36/37-16-24/25
- WGK Germany
- 2
- RTECS
- YS4550000
- TSCA
- Yes
- HS Code
- 29350090
- Toxicity
- LD50 oral in rat: 2490mg/kg
Use
Tolbutamide, 1-butyl-3-(p-tolylsulfonyl)urea (Orinase), occurs as a white, crystalline powderthat is insoluble in water and soluble in alcohol or aqueousalkali. It is stable in air.Tolbutamide is absorbed rapidly in responsive diabetic patients.The blood sugar level reaches a minimum after 5 to8 hours. It is oxidized rapidly in vivo to 1-butyl-3-(p-carboxyphenyl)sulfonylurea, which is inactive. The metabolite isfreely soluble at urinary pH; if the urine is strongly acidified,however, as in the use of sulfosalicylic acid as a protein precipitant,a white precipitate of the free acid may be formed.
26 India supplier list of "TOLBUTAMIDE"
- Product Name:Tolbutamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Tolbutamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Tolbutamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Tolbutamide
- Products Intro:Brand:sigma aldrich | Product Number:46968 | Purity:VETRANAL?,analyticalstandard
- Company Type: Trader
- Country/Region: INDIA
- Product Name:Tolbutamide
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.013550
- Company Type: Trader
- Country/Region: INDIA
- Product Name:TOLBUTAMIDE
- Company Type: Trader
- Country/Region: INDIA
- Product Name:TOLBUTAMIDE
- Company Type: Trader
- Country/Region: INDIA
- Product Name:TOLBUTAMIDE
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:TOLBUTAMIDE
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Tolbutamide
- Company Type: Reagent
- Country/Region: INDIA