ZOTAROLIMUS
ZOTAROLIMUS
- CAS:
- 221877-54-9
- MF:
- C52H79N5O12
- MW:
- 966.21
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Properties
- Melting point:
- 100-105°C
- Boiling point:
- 1016.2±75.0 °C(Predicted)
- Density
- 1.25
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO, Methanol (Slightly)
- form
- Solid
- pka
- 10.40±0.70(Predicted)
- color
- White to Pale Yellow
Safety Information
- HS Code
- 29349990
Use
Zotarolimus is a semi-synthetic macrocyclic lactone prepared from rapamycin by preparation of the 42-triflate ester, followed by displacement with tetrazole and purification of the two isomeric products. This structural change affords a less bioavailable product, a preferred profile for some applications. Like all tacrolimus analogues, zotarolimus binds to a receptor protein (FKBP12). The complex then binds to mTOR preventing it from interacting with target proteins. Zotarolimus is extensively cited in the literature with over 200 citations.
0 India supplier list of "ZOTAROLIMUS"
- Product Name:Zotarolimus
- Products Intro:Brand:pharmaffiliates | Product Number:PA2610000
- Company Type: Trader
- Country/Region: INDIA