3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine
- ₹0
- Product name: 3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine
- CAS: 1254977-87-1
- MF: C22H23F3N4
- MW: 400.44
- EINECS:
- MDL Number:MFCD22199231
- Synonyms:3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine;JNJ42153605 (on going);JNJ-42153605;JNJ42153605;CS-2446;3-(Cyclopropylmethyl)-7-(4-phenyl-1-piperidinyl)-8-(trifluorometh yl)[1,2,4]triazolo[4,3-a]pyridine;1,2,4-Triazolo[4,3-a]pyridine, 3-(cyclopropylmethyl)-7-(4-phenyl-1-piperidinyl)-8-(trifluoromethyl)-;Inhibitor,JNJ42153605,Metabotropic glutamate receptors,JNJ-42153605,inhibit,JNJ 42153605,mGluR
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
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Properties
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:30.0(Max Conc. mg/mL);74.92(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMSO:10.34(Max Conc. mg/mL);25.81(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);24.97(Max Conc. mM) form :A crystalline solid
pka :3.07±0.30(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :DMF:30.0(Max Conc. mg/mL);74.92(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.62(Max Conc. mM)
DMSO:10.34(Max Conc. mg/mL);25.81(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);24.97(Max Conc. mM) form :A crystalline solid
pka :3.07±0.30(Predicted)
color :White to off-white
Safety Information
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Description
JNJ-42153605 is a positive allosteric modulator of metabotropic glutamate receptor 2 (mGluR2; EC50 = 17 nM in CHO cells expressing the human receptor). In vivo, JNJ-42153605 (3 mg/kg) inhibits mGluR2-mediated rapid eye movement (REM) sleep in rats. It also reverses phencyclidine-induced hyperlocomotion in mice (ED50 = 5.4 mg/kg).Related product price
- JNJ 63533054
₹10954.9-44057.75 - JNJ-7706621
₹33440
Suppliers and manufacturers
career henan chemical co
ATK CHEMICAL COMPANY LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Hangzhou MolCore BioPharmatech Co.,Ltd.
TargetMol Chemicals Inc.
Aladdin Scientific
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Chunchuang (Wuhan) Technology Co., Ltd
InvivoChem
₹2.00 /1KG
3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS: 1254977-87-1
3-(cyclopropylMethyl)-7-(4-phenylpiperidin-1-yl)-8-(trifluoroMethyl)-[1,2,4]triazolo[4,3-a]pyridine CAS: 1254977-87-1