5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE
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- ₹0
- Product name: 5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE
- CAS: 163769-88-8
- MF: C22H21N3O2
- MW: 359.42
- EINECS:
- MDL Number:MFCD00354370
- Synonyms:Benz[7,8]indolizino[2,3-b]quinoxaline,5,6-dihydro-2,3-dimethoxy-6,6-dimethyl-;5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE;YM 90709;2,3-Dimethoxy-6,6-dimethyl-5,6-dihydrobenzo[7,8]indolizino[2,3-b]quinoxaline;YM 90709;YM90709;YM-90709;YM-90709,GM-CSF,inhibit,Inhibitor,Interleukin Related,IL-5,eosinophils,IL-5R,JAK2
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
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Properties
Boiling point :579.6±50.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml
form :A crystalline solid
pka :2.74±0.40(Predicted)
color :Brown to orange
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml
form :A crystalline solid
pka :2.74±0.40(Predicted)
color :Brown to orange
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
YM-90709 is a competitive antagonist of the interleukin-5 (IL-5) receptor that has IC50 values of 1 and 0.57 μM for peripheral human eosinophils and eosinophilic HL-60 clone 15 cells, respectively, in a radioligand binding assay. It inhibits IL-5-induced eosinophil survival (IC50 = 0.45 μM) and JAK2 phosphorylation in vitro. YM-90709 inhibits eosinophil and lymphocyte infiltration (ED50s = 0.32 and 0.12 mg/kg, respectively) into the brochoalveolar lavage fluid (BALF) of rats and eosinophil infiltration (ED50 = 0.05 mg/kg) into the BALF of mice in models of airway inflammation.More related product prices
371942-69-7 YM-53601 902589-96-2 BTP2 YM 26734 YM155 Centchroman DIMETHYLCYANAMIDERelated product price
- 902589-96-2
₹11506.98-46374.3 - BTP2
₹20090-89550 - YM 26734
₹13563.73-54547.18
Suppliers and manufacturers
career henan chemical co
A.J Chemicals
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Aladdin Scientific
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Bide Pharmatech Ltd.
₹1.00 /1g
5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE CAS:163769-88-8
5,6-DIHYDRO-2,3-DIMETHOXY-6,6-DIMETHYLBENZ[7,8]INDOLIZINO[2,3-B]QUINOXALINE CAS:163769-88-8