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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antidepressants, Antimanics drugs >Clomipramine hydrochloride

Clomipramine hydrochloride

Clomipramine hydrochloride Structure
  • ₹2407.3 - ₹17698.88
  • Product name: Clomipramine hydrochloride
  • CAS: 17321-77-6
  • MF: C19H24Cl2N2
  • MW: 351.31
  • EINECS:241-344-3
  • MDL Number:MFCD00069234
  • Synonyms:3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(b,f)azepinemono ;3-chloroimipraminehydrochloride ;CHLOROIMIPRAMINE HYDROCHLORIDE;CHLORIMIPRAMINE HYDROCHLORIDE;CLOMIPRAMINE HCL;CLOMIPRAMINE HYDROCHLORIDE;3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenz[b,f]azepine monohydrochloride;3-CHLORO-10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • 1ML
  • 5G
  • ManufacturerSigma-Aldrich(India)
  • Product numberC-118
  • Product descriptionClomipramine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹2407.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC7291
  • Product descriptionClomipramine hydrochloride ≥98% (HPLC), powder
  • Packaging1G
  • Price₹4514.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1720
  • Product descriptionClomipramine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹15934.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC7291
  • Product descriptionClomipramine hydrochloride ≥98% (HPLC), powder
  • Packaging5G
  • Price₹17698.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C-118 Clomipramine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹2407.3 2022-06-14 Buy
Sigma-Aldrich(India) C7291 Clomipramine hydrochloride ≥98% (HPLC), powder 1G ₹4514.03 2022-06-14 Buy
Sigma-Aldrich(India) PHR1720 Clomipramine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹15934.4 2022-06-14 Buy
Sigma-Aldrich(India) C7291 Clomipramine hydrochloride ≥98% (HPLC), powder 5G ₹17698.88 2022-06-14 Buy

Properties

Melting point :189-190°C
Flash point :9℃
storage temp. :2-8°C
solubility :H2O: 25 mg/mL
form :powder
color :white to off-white
PH :3.5～5.0（100g/l，25℃）
BCS Class :3/1
InChIKey :WIMWMKZEIBHDTH-UHFFFAOYSA-N
CAS DataBase Reference :17321-77-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P307+P311, P321,P405, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

Clomipramine is a tricyclic antidepressant, the 3-chlorinated derivative of imipramine . Like imipramine, clomipramine potently inhibits serotonin and norepinephrine reuptake (Kis = 7.4 and 96 nM, respectively). It also is an antagonist at histamine, muscarinic acetylcholine, α1-adrenergic, and dopamine receptors (Kds = 31, 37, 38, and 190 nM for H1, M1, α1, and D2, respectively).

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Suppliers and manufacturers

SKVen Technologies Pvt.Ltd. Global Pharma R L Fine Chem Pvt. Ltd Mankind Pharma Limited Sun Pharmaceutical Industries Ltd Almon Industries Ralington Pharma Biophore India Pharmaceuticals Pvt Ltd Molsyns Research Flowchem Pharma Pvt Ltd